4-methyl-3-(2-propenyl)cyclohexanone

Base Information

• Chemical Name: 4-methyl-3-(2-propenyl)cyclohexanone
• CAS No.: 911800-19-6
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.236
• Mol file: 911800-19-6.mol

Synonyms:4-methyl-3-(2-propenyl)cyclohexanone

Chemical Property of 4-methyl-3-(2-propenyl)cyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-methyl-3-(2-propenyl)cyclohexanone

There total 1 articles about 4-methyl-3-(2-propenyl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-2-cyclohexenone (75337-05-2,79980-78-2,101758-35-4,5515-76-4) + allyl-trimethyl-silane (762-72-1) → 4-methyl-3-(2-propenyl)cyclohexanone (911800-19-6)

Guidance literature:

With titanium tetrachloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, -78 deg C, 5 min, 2.) CH₂Cl₂, -78 deg C, 45 min;

DOI:10.1016/0040-4020(96)00544-3

Reference yield:

4-methyl-3-(2-propenyl)cyclohexanone (911800-19-6) → 4-methyl-3-propylcyclohexanone (84877-76-9) + 4-methyl-3-propylcyclohexanone (84877-75-8)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; Title compound not separated from byproducts;

DOI:10.1021/ja00346a041

Reference yield:

4-methyl-3-(2-propenyl)cyclohexanone (911800-19-6) → 4-Bromo-benzoic acid (3R,3aS,4R,7R,7aS)-3,7-dimethyl-octahydro-inden-4-yl ester

Guidance literature:

Multi-step reaction with 9 steps

1: 95 percent / TsOH / benzene / 16 h / Heating

2: 1.) BH₃*THF, 2.) aq. NaOH, 30percent H₂O₂ / 1.) THF, RT, 1.4 h, 2.) THF, from 30 to 50 deg C, 1 h

3: 1.) (COCl)2, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, 5 min, 2.) CH₂Cl₂, 15 min

4: 1.) Mg / 2.) ether, RT, 2.4 h

5: 95 percent / CrO₃, H₂SO₄ / acetone / 1 h / 0 °C

6: 14.4 percent / KOH / methanol / 2.3 h / 50 °C

7: 14.3 percent / H₂ / 10percent Pd/C / hexane / Ambient temperature

8: 96 percent / NaBH₄ / methanol / 0.58 h / Ambient temperature

9: 67 percent / Et₃N, dimethylaminopyridine / CH₂Cl₂ / 13.3 h / Ambient temperature

With chromium(VI) oxide; dmap; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; borane-THF; oxalyl dichloride; sulfuric acid; hydrogen; dihydrogen peroxide; toluene-4-sulfonic acid; magnesium; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In methanol; hexane; dichloromethane; acetone; benzene;

DOI:10.1016/0040-4020(96)00544-3

upstream raw materials:

4-methyl-2-cyclohexenone

allyl-trimethyl-silane

Downstream raw materials:

4-methyl-3-propylcyclohexanone

4-methyl-3-propylcyclohexanone