3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Base Information

Chemical Name:3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine
CAS No.:92406-44-5
Molecular Formula:C10H10 Cl N3
Molecular Weight:207.66
Hs Code.:2933199090
European Community (EC) Number:871-937-8
DSSTox Substance ID:DTXSID40536893
Wikidata:Q82411712
Mol file:92406-44-5.mol

Synonyms:92406-44-5;3-(3-CHLOROPHENYL)-1-METHYL-1H-PYRAZOL-5-AMINE;5-(3-CHLORO-PHENYL)-2-METHYL-2H-PYRAZOL-3-YLAMINE;5-(3-CHLOROPHENYL)-2-METHYLPYRAZOL-3-AMINE;SCHEMBL4765637;DTXSID40536893;AB13058;5-(3-chlorophenyl)-2-methyl-3-pyrazolamine;5-(3-chlorophenyl)-2-methyl-pyrazol-3-amine;EN300-1149110;A844224

Suppliers and Price of 3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(3-Chloro-phenyl)-2-methyl-2H-pyrazol-3-ylamine
100mg
$ 285.00

Labseeker
3-(3-CHLOROPHENYL)-1-METHYL-1H-PYRAZOL-5-AMINE 95
10g
$ 2017.00

Labseeker
3-(3-CHLOROPHENYL)-1-METHYL-1H-PYRAZOL-5-AMINE 95
2g
$ 1283.00

Crysdot
3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine 95+%
1g
$ 623.00

Chemenu
5-(3-Chloro-phenyl)-2-methyl-2H-pyrazol-3-ylamine 95%
1g
$ 583.00

Anichem
5-(3-Chlorophenyl)-2-methyl-2H-pyrazol-3-ylamine >95%
1g
$ 300.00

Alichem
3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine
1g
$ 522.08

Total 8 raw suppliers

Chemical Property of 3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Chemical Property:

PSA：43.84000
LogP:2.90390
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:207.0563250
Heavy Atom Count:14
Complexity:200

Purity/Quality:

97% ^*data from raw suppliers

5-(3-Chloro-phenyl)-2-methyl-2H-pyrazol-3-ylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=CC(=N1)C2=CC(=CC=C2)Cl)N

Technology Process of 3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine

There total 4 articles about 3-(3-Chlorophenyl)-1-methyl-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 21667-62-9
3-chlorobenzoylacetonitrile

: 60-34-4
methylhydrazine

: 92406-44-5
3-(3-chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Guidance literature:: With triethylamine; In methanol; at 120 ℃; for 1.5h; Microwave irradiation; Sealed tube;
DOI:10.1021/acs.jmedchem.0c01777

Reference yield: 46.0%

: 22038-72-8,26981-93-1,51943-20-5
methyldiazene

: 21667-62-9
3-chlorobenzoylacetonitrile

: 92406-44-5
3-(3-chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Guidance literature:: In methanol; at 120 ℃; for 1h; Microwave irradiation;

Reference yield:

: 2905-65-9
methyl 3-chlorobenzoate

: 92406-44-5
3-(3-chlorophenyl)-1-methyl-1H-pyrazol-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0 - 80 °C

1.2: 0.5 h / 80 °C

2.1: methanol / 1 h / 120 °C / Microwave irradiation

With sodium hydride; In tetrahydrofuran; methanol;