1'-methylbenzyl 2,4,6-triisopropylbenzoate

Base Information

• Chemical Name: 1'-methylbenzyl 2,4,6-triisopropylbenzoate
• CAS No.: 77256-62-3
• Molecular Formula: C₂₄H₃₂O₂
• Molecular Weight: 352.517
• Mol file: 77256-62-3.mol

Synonyms:1'-methylbenzyl 2,4,6-triisopropylbenzoate

Chemical Property of 1'-methylbenzyl 2,4,6-triisopropylbenzoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1'-methylbenzyl 2,4,6-triisopropylbenzoate

There total 7 articles about 1'-methylbenzyl 2,4,6-triisopropylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-Phenylethanol (98-85-1,13323-81-4) + 2,4,6-triisopropylbenzoyl chloride (57199-00-5) → 1'-methylbenzyl 2,4,6-triisopropylbenzoate (77256-62-3)

Guidance literature:

1-Phenylethanol; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.25h; Inert atmosphere;

2,4,6-triisopropylbenzoyl chloride; In tetrahydrofuran; mineral oil; at 50 ℃; for 72h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b02753

Reference yield: 80.0%

ethylbenzene (100-41-4,27536-89-6) + 2,4,6-triisopropylbenzoic acid (49623-71-4) → 1'-methylbenzyl 2,4,6-triisopropylbenzoate (77256-62-3)

Guidance literature:

With di-tert-butyl peroxide; C₁₁H₂₃N₂⁽¹⁺⁾*Br₄Fe^(1-); at 110 ℃; for 24h;

DOI:10.1021/acs.orglett.7b00148

Reference yield: 43.0%

1-Phenylethanol (98-85-1,13323-81-4) + 2,4,6-triisopropylbenzoic acid (49623-71-4) → 1'-methylbenzyl 2,4,6-triisopropylbenzoate (77256-62-3)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In toluene; 1.) 0 deg C, 1 h, 2.) room temp., 3 h;

upstream raw materials:

benzyl 2,4,6-triisopropylbenzoate

methyl iodide

1-Phenylethanol

2,4,6-triisopropylbenzoic acid

Downstream raw materials:

2-(2-phenylpropyl) 2,4,6-triisopropylbenzoate

Methyl 2-phenyl-2-(2,4,6-triisopropylbenzyloxy)propionate

2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol

(R)-1-phenyl-1,2-ethanediol