Technology Process of C10H11Br
There total 1 articles about C10H11Br which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methylmagnesium bromide; 4-bromo-N-methoxy-N,2-dimethylbenzamide;
With
ethyltriphenylphosphonium bromide; sodium hexamethyldisilazane;
DOI:10.1016/j.bmcl.2012.03.067
- Guidance literature:
-
With
C29H33Cl2CoN3O; sodium tri-sec-butylborohydride;
In
tetrahydrofuran;
at 25 ℃;
for 5h;
Overall yield = 73 %; enantioselective reaction;
Inert atmosphere;
DOI:10.1021/acscatal.6b02278
- Guidance literature:
-
Multi-step reaction with 7 steps
1: n-butyllithium
2: tris-triphenylphosphine ruthenium(II) chloride; hydrogen
3: PhMe2NBr3
4: sodium diformamide
5: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / chloroform
6: Lawessons reagent; pyridine / toluene / 100 °C
7: tetrabutyl ammonium fluoride / tetrahydrofuran
With
Lawessons reagent; pyridine; n-butyllithium; tris-triphenylphosphine ruthenium(II) chloride; sodium diformamide; tetrabutyl ammonium fluoride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; chloroform; toluene;
DOI:10.1016/j.bmcl.2012.03.067