4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide

Base Information

• Chemical Name: 4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide
• CAS No.: 957793-55-4
• Molecular Formula: C₂₅H₃₆N₂O₃Si
• Molecular Weight: 440.658
• Mol file: 957793-55-4.mol

Synonyms:4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide

Chemical Property of 4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide

There total 1 articles about 4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(hydroxymethyl)-N'-(4-isobutylbenzoyl)benzohydrazide (957793-54-3) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide (957793-55-4)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 - 25 ℃; for 72h;

Reference yield: 100.0%

4-(tert-butyl-dimethyl-silanyloxymethyl)-benzoic acid N'-(4-isobutyl-benzoyl)-hydrazide (957793-55-4) → 2-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]-5-(4-isobutylphenyl)-1,3,4-oxadiazole (957793-57-6)

Guidance literature:

With methoxycarbonylsulfamoyl-triethylammmonium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide; at 110 ℃; for 16h;

upstream raw materials:

4-(hydroxymethyl)-N'-(4-isobutylbenzoyl)benzohydrazide

tert-butyldimethylsilyl chloride

Downstream raw materials:

2-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]-5-(4-isobutylphenyl)-1,3,4-oxadiazole