(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Base Information

Chemical Name:(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester
CAS No.:413193-14-3
Molecular Formula:C₂₂H₂₅NO₅
Molecular Weight:383.444
Hs Code.:

Synonyms:(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Suppliers and Price of (4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

There total 5 articles about (4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 413193-10-9
(4-Methoxy-phenyl)-carbamic acid (Z)-(R)-4-hydroxy-1-((S)-1-hydroxy-ethyl)-2-methyl-but-2-enyl ester

: 100-51-6,185532-71-2
benzyl alcohol

: 413193-14-3
(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: (4-Methoxy-phenyl)-carbamic acid (Z)-(R)-4-hydroxy-1-((S)-1-hydroxy-ethyl)-2-methyl-but-2-enyl ester; With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dimethyl sulfoxide; at 25 ℃; for 0.5h;

benzyl alcohol; With camphor-10-sulfonic acid; In dichloromethane; at 25 ℃; for 2h; Further stages.;
DOI:10.1021/ja012126h

Reference yield:

: 413193-02-9
2-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-en-3-ol

: 413193-14-3
(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 79 percent / DBU / CH₂Cl₂ / 10 h / 25 °C

2.1: 80 percent / TBAF / tetrahydrofuran / 1 h / 25 °C

3.1: IBX / tetrahydrofuran; dimethylsulfoxide / 0.5 h / 25 °C

3.2: 90 percent / CSA / CH₂Cl₂ / 2 h / 25 °C

With tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ja012126h

Reference yield:

: 413193-06-3
(4-methoxy-phenyl)-carbamic acid 1-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-(tert-butyl-diphenyl-silanyloxy)-2-methyl-but-2-enyl ester

: 413193-14-3
(4-Methoxy-phenyl)-carbamic acid (2S,3R,6S)-6-benzyloxy-2,4-dimethyl-3,6-dihydro-2H-pyran-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: 80 percent / TBAF / tetrahydrofuran / 1 h / 25 °C

2.1: IBX / tetrahydrofuran; dimethylsulfoxide / 0.5 h / 25 °C

2.2: 90 percent / CSA / CH₂Cl₂ / 2 h / 25 °C

With tetrabutyl ammonium fluoride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/ja012126h