Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

Base Information

Chemical Name:Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one
CAS No.:1282453-21-7
Molecular Formula:C₁₉H₁₈FNO
Molecular Weight:295.356
Hs Code.:

Synonyms:Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

Chemical Property:

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Technology Process of Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

There total 1 articles about Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1234356-88-7
(R)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 1282453-21-7
Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

Guidance literature:: In isopropyl alcohol; at 80 - 85 ℃; for 19h; Large scale;

Reference yield: 81.0%

: 1282453-21-7
Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one

: 1-(3-(2-hydroxyethyl)phenyl)guanidine methanesulfonate

: C₂₆H₂₂FN₃O*ClH

Guidance literature:: 1-(3-(2-hydroxyethyl)phenyl)guanidine methanesulfonate; With sodium ethanolate; In 2-methyltetrahydrofuran; ethanol; at 20 - 25 ℃; for 2h; Large scale;

Missing (R)-2-((dimethylamino)methylene)-4-(2-fluorophenyl)-3,4-dihydronaphthalen-1(2H)-one; In 2-methyltetrahydrofuran; ethanol; at 75 - 80 ℃; for 36h; Large scale;

With hydrogenchloride; In 2-methyltetrahydrofuran; water; at 60 - 65 ℃; for 3.9h; Large scale;