2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1147105-68-7
• Molecular Formula: C₁₄H₂₁BO₃
• Molecular Weight: 248.13
• Mol file: 1147105-68-7.mol

Synonyms:2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

• Boiling Point: 336.9±25.0 °C(Predicted)
• Density: 1.01±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

4-EthoxyphenylboronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 6 articles about 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

para-ethoxytosyloxybenzene + bis(pinacol)diborane (73183-34-3) → 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1147105-68-7)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium phosphate; tricyclohexylphosphine; In tetrahydrofuran; at 20 ℃; Reagent/catalyst; Catalytic behavior; Glovebox; Inert atmosphere;

DOI:10.1002/ejoc.201701300

Reference yield: 75.0%

1-ethoxy-4-iodobenzene (699-08-1) + bis(pinacol)diborane (73183-34-3) → 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1147105-68-7)

Guidance literature:

With silver fluoride; In acetonitrile; at 20 ℃; Sealed tube; UV-irradiation; Inert atmosphere;

DOI:10.1016/j.jcat.2021.08.035

Reference yield: 70.0%

1-chloro-4-ethoxybenzene (622-61-7) + bis(pinacol)diborane (73183-34-3) → 2-(4-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1147105-68-7)

Guidance literature:

With pyridine-4-carbonitrile; potassium phosphate; sodium oxalate; 2,4,5-tri(9H-carbazol-9-yl)-6-(ethyl(phenyl)amino)isophthalonitrile; In acetonitrile; at 20 ℃; for 24h; Irradiation; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.1c05994

upstream raw materials:

Phenetole

bis(pinacol)diborane

4-bromoethoxybenzene

2,3-dimethyl-2,3-butane diol

Downstream raw materials:

2-bromo-6-(4-ethoxyphenyl)pyridine