[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Base Information

Chemical Name:[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester
CAS No.:1315312-40-3
Molecular Formula:C₂₅H₂₅N₃O₅
Molecular Weight:447.491
Hs Code.:

Synonyms:[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Suppliers and Price of [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

There total 5 articles about [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1315312-38-9
[4-(5-chloro-oxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid tert-butyl ester

: 108-95-2,27073-41-2
phenol

: 1315312-40-3
[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Guidance literature:: phenol; With sodium hydride; In N,N-dimethyl acetamide; at 20 ℃; for 0.5h; Inert atmosphere;

[4-(5-chloro-oxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid tert-butyl ester; In N,N-dimethyl acetamide; at 20 ℃; for 1.5h;

With citric acid; In N,N-dimethyl acetamide; water; pH=7;

Reference yield:

: 1315312-37-8
4-(5-chloro-oxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethyl-phenol

: 1315312-40-3
[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 4.5 h / 20 - 50 °C

2.1: sodium hydride / N,N-dimethyl acetamide / 0.5 h / 20 °C / Inert atmosphere

2.2: 1.5 h / 20 °C

2.3: pH 7

With sodium hydride; potassium carbonate; In N,N-dimethyl acetamide; N,N-dimethyl-formamide;

Reference yield:

: 1315312-36-7
5-chloro-2-(4-methoxy-3,5-dimethyl-phenyl)-oxazolo[5,4-d]pyrimidine

: 1315312-40-3
[2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: boron tribromide / dichloromethane / 2.17 h / 0 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 4.5 h / 20 - 50 °C

3.1: sodium hydride / N,N-dimethyl acetamide / 0.5 h / 20 °C / Inert atmosphere

3.2: 1.5 h / 20 °C

3.3: pH 7

With boron tribromide; sodium hydride; potassium carbonate; In dichloromethane; N,N-dimethyl acetamide; N,N-dimethyl-formamide;