2-BENZYLOXY-2-METHYLPROPAN-1-OL

Base Information

• Chemical Name: 2-BENZYLOXY-2-METHYLPROPAN-1-OL
• CAS No.: 91968-71-7
• Molecular Formula: C11H16 O2
• Molecular Weight: 180.247
• Hs Code.: 2909499000
• Mol file: 91968-71-7.mol

Synonyms:1-Propanol,2-(benzyloxy)-2-methyl- (7CI); 2-Methyl-2-(phenylmethoxy)propan-1-ol

Chemical Property of 2-BENZYLOXY-2-METHYLPROPAN-1-OL

Chemical Property:

• Vapor Pressure: 0.00266mmHg at 25°C
• Refractive Index: 1.514
• Boiling Point: 274.2°Cat760mmHg
• PKA: 15.18±0.10(Predicted)
• Flash Point: 109.4°C
• PSA: 29.46000
• Density: 1.025g/cm³
• LogP: 1.97410
• Water Solubility.: Immiscible with water.

Purity/Quality:

98%Min ^*data from raw suppliers

2-Benzyloxy-2-methylpropan-1-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Benzyloxy-2-methyl-1-propanol is used as a building block in organic synthesis. 2-Benzyloxy-2-methylpropan-1-ol useful for synthesis of heterocyclic compounds.

Technology Process of 2-BENZYLOXY-2-METHYLPROPAN-1-OL

There total 7 articles about 2-BENZYLOXY-2-METHYLPROPAN-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

benzyl 2-(benzyloxy)-2-methylpropanoate (347400-73-1) → 2-(benzyloxy)-2-methylpropan-1-ol (91968-71-7)

Guidance literature:

benzyl 2-(benzyloxy)-2-methylpropanoate; With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃;

With sodium hydroxide; water; In tetrahydrofuran;

Reference yield: 38.51%

2-benzyloxy-2-methylpropanoic acid methyl ester (87122-86-9) → 2-(benzyloxy)-2-methylpropan-1-ol (91968-71-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

Reference yield:

2-(benzyloxy)-2-methylpropanoic acid (87122-87-0) → 2-(benzyloxy)-2-methylpropan-1-ol (91968-71-7)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1139/v64-154

upstream raw materials:

2-(benzyloxy)-2-methylpropanoic acid

benzyl bromide

benzyl alcohol

benzyl 2-(benzyloxy)-2-methylpropanoate

Downstream raw materials:

2-(benzyloxy)-2-methylpropanal

2-[2-(benzyloxy)-2-methylpropoxy]-N-{(3E)-5-tert-butyl-1-methyl-2-[(2R)-tetrahydrofuran-2-ylmethyl]-1,2-dihydro-3H-pyrazol-3-ylidene}-5-(trifluoromethyl)benzamide

2-Methyl-1,2-propanediol