Technology Process of C52H58N4O3
There total 4 articles about C52H58N4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-[tris-(4-tert-butylphenyl)methyl]phenol;
With
potassium carbonate;
In
acetonitrile;
at 60 ℃;
for 0.333333h;
Inert atmosphere;
Schlenk technique;
2-((3-(2-azidoethoxy)phenoxy)methyl)-6-(bromomethyl)pyridine;
In
acetonitrile;
for 24.1667h;
Reflux;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/ol400221h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; ethanol / 10 h / 20 °C / Inert atmosphere; Schlenk technique
2.1: sodium azide / N,N-dimethyl-formamide / 10 h / 60 °C / Inert atmosphere; Schlenk technique
3.1: potassium carbonate / acetonitrile / 0.33 h / 60 °C / Inert atmosphere; Schlenk technique
3.2: 24.17 h / Reflux; Inert atmosphere; Schlenk technique
4.1: potassium carbonate / acetonitrile / 0.33 h / 60 °C / Inert atmosphere; Schlenk technique
4.2: 24.17 h / Reflux; Inert atmosphere; Schlenk technique
With
sodium azide; palladium 10% on activated carbon; hydrogen; potassium carbonate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ol400221h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium azide / N,N-dimethyl-formamide / 10 h / 60 °C / Inert atmosphere; Schlenk technique
2.1: potassium carbonate / acetonitrile / 0.33 h / 60 °C / Inert atmosphere; Schlenk technique
2.2: 24.17 h / Reflux; Inert atmosphere; Schlenk technique
3.1: potassium carbonate / acetonitrile / 0.33 h / 60 °C / Inert atmosphere; Schlenk technique
3.2: 24.17 h / Reflux; Inert atmosphere; Schlenk technique
With
sodium azide; potassium carbonate;
In
N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ol400221h
