o-Toluenesulfonic acid, phenyl ester

Base Information

• Chemical Name: o-Toluenesulfonic acid, phenyl ester
• CAS No.: 91903-33-2
• Molecular Formula: C13H12 O3 S
• Molecular Weight: 248.29758
• Mol file: 91903-33-2.mol

Synonyms:o-Toluenesulfonicacid, phenyl ester (6CI,7CI)

Chemical Property of o-Toluenesulfonic acid, phenyl ester

Chemical Property:

• PSA: 51.75000
• LogP: 3.84350

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of o-Toluenesulfonic acid, phenyl ester

There total 2 articles about o-Toluenesulfonic acid, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenol (108-95-2,27073-41-2) + Toluene-2-sulfonyl chloride (133-59-5) → phenyl o-toluenesulfonate (91903-33-2)

Guidance literature:

With triethylamine; In benzene; at 30 ℃; Rate constant;

Reference yield:

sodium phenoxide (139-02-6) + Toluene-2-sulfonyl chloride (133-59-5) → phenyl o-toluenesulfonate (91903-33-2)

Guidance literature:

Reference yield:

phenyl o-toluenesulfonate (91903-33-2) → 2-[2-(2-Sulfino-phenyl)-ethyl]-benzenesulfonic acid phenyl ester

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -68 - 20 ℃; for 4.66667h;

DOI:10.1021/jo00350a095

upstream raw materials:

sodium phenoxide

Toluene-2-sulfonyl chloride

phenol

Refernces

• 1、 Maksimenko, N. N.,Rubleva, L. I.. "REACTIVITY OF STERICALLY HINDERED DERIVATIVES OF AROMATIC SULFONIC ACIDS. III. EFFECT OF THE STRUCTURE OF ARENESULFONYL CHLORIDES ON THE KINETICS OF CATALYTIC SULFONYLATION OF PHENOL". . p. 694 - 697. Retrieved 2007/10/02.