1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE

Base Information

• Chemical Name: 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE
• CAS No.: 96221-84-0
• Molecular Formula: C₁₇H₂₀N₂O
• Molecular Weight: 268.359
• Mol file: 96221-84-0.mol

Synonyms:1-[2-(Benzyloxy)phenyl]piperazine;1-[2-(Phenylmethoxy)phenyl]piperazine

Chemical Property of 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE

Chemical Property:

• PSA: 24.50000
• LogP: 3.06900

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Benzyloxy-phenyl)-piperazine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE

There total 1 articles about 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-(benzyloxy)aniline (20012-63-9) → 1-(2-(benzyloxy)phenyl)piperazine (96221-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 8 h / 150 °C / Inert atmosphere

2: sodium carbonate

With sodium carbonate;

DOI:10.1016/j.bmcl.2014.01.070

Reference yield:

C11H13BrO3 (1159689-74-3) + 1-(2-(benzyloxy)phenyl)piperazine (96221-84-0) → C21H27BrN2O4 (1542226-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 8 h / Reflux

2: boron tribromide / dichloromethane / 2 h / -78 °C

With ethanol; boron tribromide; In dichloromethane;

DOI:10.1016/j.bmcl.2014.01.070

upstream raw materials:

o-(benzyloxy)aniline

Downstream raw materials:

C₂₁H₂₇BrN₂O₄

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