dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester

Base Information

• Chemical Name: dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester
• CAS No.: 920509-73-5
• Molecular Formula: C₂₇H₃₁Cl₂NO₂SSi
• Molecular Weight: 532.606
• Mol file: 920509-73-5.mol

Synonyms:dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester

Chemical Property of dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester

There total 5 articles about dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

dimethylthiocarbamic acid O-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester (920509-72-4) → dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester (920509-73-5)

Guidance literature:

at 190 - 200 ℃; for 24h;

Reference yield:

4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenol (920509-71-3) → dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester (920509-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane / N,N-dimethyl-formamide / 18 h / 25 °C / Inert atmosphere

2: 24 h / 199 - 200 °C / Inert atmosphere

With 1,4-diaza-bicyclo[2.2.2]octane; In N,N-dimethyl-formamide;

DOI:10.1021/jm4019299

Reference yield:

2-(3,5-dichloro-4-hydroxyphenyl)ethanol (115150-58-8) → dimethylthiocarbamicacid S-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester (920509-73-5)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 18 h / 25 °C / Inert atmosphere

2: 1,4-diaza-bicyclo[2.2.2]octane / N,N-dimethyl-formamide / 18 h / 25 °C / Inert atmosphere

3: 24 h / 199 - 200 °C / Inert atmosphere

With 1,4-diaza-bicyclo[2.2.2]octane; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm4019299

upstream raw materials:

dimethylthiocarbamic acid O-{4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenyl}ester

4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-2,6-dichlorophenol

Methyl 4-hydroxyphenylacetate

(3,5-dichloro-4-hydroxyphenyl)acetic acid methyl ester

Downstream raw materials:

2-(3,5-dichloro-4-mercaptophenyl)ethanol