(-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

Base Information

Chemical Name:(-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole
CAS No.:132959-42-3
Molecular Formula:C₁₇H₂₁NO₂
Molecular Weight:271.359
Hs Code.:

Synonyms:(-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

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Chemical Property of (-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

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Technology Process of (-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

There total 1 articles about (-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 3400-90-6
4-oxo-4-cyclopentylbutanoic acid

: 56613-80-0
D-2-phenylglycinol

: 132959-42-3
(-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

Guidance literature:: In toluene; Heating;
DOI:10.1021/jo00007a011 DOI:10.1021/jo00032a012

Reference yield: 88.0%

: 132959-42-3
(-)-(3R,7aR)-3-Phenyl-5-oxo-7a-cyclopentyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

: 139564-37-7
(+)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(S)-cyclopentyl-2-pyrrolidinone

Guidance literature:: With triethylsilane; titanium tetrachloride; In dichloromethane; Further byproducts given. Yields of byproduct given; a) -78 deg C, 1.5 h, b) r.t., 12 h;
DOI:10.1021/jo00032a012