3400-90-6Relevant academic research and scientific papers
Synthesis of γ-, δ-, and ε-lactams by asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)iminoesters
Guijarro, David,Pablo, Oscar,Yus, Miguel
, p. 3647 - 3654 (2013/05/22)
Highly enantiomerically enriched γ- and δ-lactams have been prepared by a simple and very efficient procedure that involves the asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)iminoesters followed by desulfinylation of the nitrogen atom and spo
Efficient regioselective oxetane formation during photochemical transformation of spiro[4. n]-2,5-Diones
Sudini, Ravinder R.,Saravanan,Kumar, Pradeep
, p. 3263 - 3273 (2007/10/03)
The irradiation of a variety of spirodiones (3) in the presence of carbonyl compounds led to the formation of oxetanes (6) regioselectively, which upon hydrolysis afforded the corresponding ketoacids (7) in excellent yields.
4-(trans-4-methylcyclohexyl)-4-oxobutyric acid (JTT-608). A new class of antidiabetic agent
Shinkai, Hisashi,Ozeki, Hidekazu,Motomura, Takahisa,Ohta, Takeshi,Furukawa, Noboru,Uchida, Itsuo
, p. 5420 - 5428 (2007/10/03)
During an investigation of drugs for improving the β-cell response to glucose, we found that 4-cyclohexyl-4-oxobutyric acid selectively improved glucose-stimulated insulin release and glucose tolerance in both normal and diabetic rats. A series of 4-cyclo
