Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)

Base Information

Chemical Name:Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)
CAS No.:91622-97-8
Molecular Formula:C10H13 N3
Molecular Weight:175.23032
Hs Code.:
Mol file:91622-97-8.mol

Synonyms:Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI);5,6,6A,7,8,9-HEXAHYDROPYRIDO[3,2-E]PYRROLO[1,2-A]PYRAZINE

Suppliers and Price of Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5,6,6a,7,8,9-hexahydro-Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine 97.00%
25G
$ 13300.00

Total 3 raw suppliers

Chemical Property of Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)

Chemical Property:

PSA：28.16000
LogP:1.67890

Purity/Quality:: 5,6,6a,7,8,9-hexahydro-Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI)

There total 5 articles about Pyrido[3,2-e]pyrrolo[1,2-a]pyrazine, 5,6,6a,7,8,9-hexahydro- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 91622-91-2
6a,7,8,9-tetrahydropyrido<3,2-e>pyrrolo<1,2-a>pyrazin-6(5H)-one

: 91622-97-8
5,6,6a,7,8,9-hexahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 2.25h;
DOI:10.1002/jhet.4270

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 91622-97-8
5,6,6a,7,8,9-hexahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazine

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / triethylamine / dimethylsulfoxide / 18 h / 60 °C

2: 56 percent / glacial acetic acid, iron powder / 3 h / 60 - 65 °C

3: 65 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; iron; acetic acid; triethylamine; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide;
DOI:10.1021/jm00378a039

Reference yield:

: 36976-98-4
N-(3-nitro-2-pyridinyl)pyrrolidine-2-carboxylic acid

: 91622-97-8
5,6,6a,7,8,9-hexahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / glacial acetic acid, iron powder / 3 h / 60 - 65 °C

2: 65 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; iron; acetic acid; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00378a039