2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine

Base Information

Chemical Name:2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine
CAS No.:91557-43-6
Molecular Formula:C₁₂H₁₆N₂O₂
Molecular Weight:220.271
Hs Code.:
DSSTox Substance ID:DTXSID60470265
Wikidata:Q82298295
Mol file:91557-43-6.mol

Synonyms:91557-43-6;2-(4,7-DIMETHOXY-1H-INDOL-3-YL)-ETHYLAMINE;2-(4,7-dimethoxy-1H-indol-3-yl)ethanamine;Methylmitro guanidine;DTXSID60470265;AKOS015965963;2-(4,7-Dimethoxy-1H-indol-3-yl)ethan-1-amine

Suppliers and Price of 2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4,7-DIMETHOXY-1H-INDOL-3-YL)-ETHYLAMINE 95.00%
5MG
$ 503.32

AccelPharmtech
2-(4,7-dimethoxy-1H-indol-3-yl)ethanamine 97.00%
5G
$ 3230.00

AccelPharmtech
2-(4,7-dimethoxy-1H-indol-3-yl)ethanamine 97.00%
1G
$ 1890.00

Total 6 raw suppliers

Chemical Property of 2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine

Chemical Property:

PSA：60.27000
LogP:2.38660
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:225

Purity/Quality:

99% ^*data from raw suppliers

2-(4,7-DIMETHOXY-1H-INDOL-3-YL)-ETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=CNC2=C(C=C1)OC)CCN

Technology Process of 2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine

There total 9 articles about 2-(4,7-Dimethoxy-1H-indol-3-YL)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15109-37-2
(4,7-dimethoxy-1H-indol-3-yl)acetonitrile

: 91557-43-6
2-(4,7-dimethoxy-1H-indol-3-yl)ethylamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1021/jm051247f

Reference yield:

: 23876-39-3
4,7-dimethoxylindole

: 91557-43-6
2-(4,7-dimethoxy-1H-indol-3-yl)ethylamine

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid / H₂O / 3 h / 20 °C

2: CH₂Cl₂; toluene / 20 °C

3: 5.67 g / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

4: LiAlH₄ / diethyl ether; CH₂Cl₂ / 0.5 h / 20 °C

With lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; water; toluene;
DOI:10.1021/jm051247f

Reference yield:

: (E)-4,7-dimethoxy-3-(2-nitrovinyl)indole

: 91557-43-6
2-(4,7-dimethoxy-1H-indol-3-yl)ethylamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; dichloromethane; at 20 ℃; for 1h;
DOI:10.1016/S0040-4039(01)00258-1