2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene

Base Information

• Chemical Name: 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene
• CAS No.: 1273542-60-1
• Molecular Formula: C₁₈H₁₉Br₃O₄
• Molecular Weight: 539.058
• Mol file: 1273542-60-1.mol

Synonyms:2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene

Chemical Property of 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene

There total 2 articles about 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-bromo-4,5-dimethoxy-toluene (68278-85-3) + (2,3-dibromo-4,5-dimethoxyphenyl)methanol (4950-08-7) → 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene (1273542-60-1)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2013.03.037

Reference yield:

2,3-dibromo-4,5-dimethoxybenzaldehyde (70625-29-5) → 2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene (1273542-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; sodium tetrahydroborate / Cooling with ice

2: aluminum (III) chloride / dichloromethane / Cooling with ice

With methanol; aluminum (III) chloride; sodium tetrahydroborate; In dichloromethane;

Reference yield:

2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene (1273542-60-1) → {3-bromo-2-[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-4,5-dimethoxyphenyl}methanol (1238891-85-4)

Guidance literature:

2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene; With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; Irradiation;

With potassium carbonate; In 1,4-dioxane; water; at 90 ℃;

DOI:10.3390/md11020350

upstream raw materials:

3-bromo-4,5-dimethoxy-toluene

(2,3-dibromo-4,5-dimethoxyphenyl)methanol

2,3-dibromo-4,5-dimethoxybenzaldehyde

Downstream raw materials:

{3-bromo-2-[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-4,5-dimethoxyphenyl}methanol

3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(isobutoxymethyl)-benzyl]-benzene-1,2-diol

2,3-dibromo-1-[2'-bromo-6'-(2-bromo-4,5-dimethoxybenzyl)-3',4'-dimethoxybenzyl]-4,5-dimethoxybenzene

3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol