3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol

Base Information

• Chemical Name: 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol
• CAS No.: 1297595-93-7
• Molecular Formula: C₁₇H₁₇Br₃O₅
• Molecular Weight: 541.031
• Mol file: 1297595-93-7.mol

Synonyms:3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol

Chemical Property of 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol

There total 11 articles about 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propan-1-ol (71-23-8) + {3-bromo-2-[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-4,5-dimethoxyphenyl}methanol (1238891-85-4) → 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol (1297595-93-7)

Guidance literature:

{3-bromo-2-[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-4,5-dimethoxyphenyl}methanol; With boron tribromide; In dichloromethane; at 0 - 20 ℃;

propan-1-ol; With phosphoric acid; In dichloromethane; for 12h; Reflux;

Reference yield:

propan-1-ol (71-23-8) + 2,2′,3-tribromo-3′,4,4′,5-tetrahydroxy-6′-hydroxymethyldiphenylmethane → 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol (1297595-93-7)

Guidance literature:

With phosphoric acid; for 2h; Reflux;

DOI:10.1016/j.ejmech.2013.03.037

Reference yield:

3-bromo-4,5-dimethoxy-toluene (68278-85-3) → 3,4-dibromo-5-[2'-bromo-3',4'-dihydroxy-6'-(propoxymethyl)-benzyl]-benzene-1,2-diol (1297595-93-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: aluminum (III) chloride / dichloromethane / Cooling with ice

2.1: potassium carbonate; 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide; water / tetrachloromethane; 1,4-dioxane / 90 °C / Photolysis

3.1: boron tribromide / dichloromethane / 0 - 20 °C

3.2: 12 h / Reflux

With aluminum (III) chloride; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water; boron tribromide; potassium carbonate; In 1,4-dioxane; tetrachloromethane; dichloromethane;

upstream raw materials:

2,3-dibromo-4,5-dimethoxybenzaldehyde

2,3-dibromo-1-(2'-bromo-3',4'-dimethoxy-6'-methylbenzyl)-4,5-dimethoxy benzene

5-bromo-4-hydroxy-3-methoxybenzaldehyde

vanillin