2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal

Base Information

• Chemical Name: 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal
• CAS No.: 222408-75-5
• Molecular Formula: C₂₆H₃₆O₄S₂
• Molecular Weight: 476.701
• Mol file: 222408-75-5.mol

Synonyms:2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal

Chemical Property of 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal

There total 2 articles about 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,5-O-isopropylidene-D-xylose diethyl dithioacetal (16885-46-4) + benzyl bromide (100-39-0) → 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal (222408-75-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 ℃;

DOI:10.1080/07328309908543989

Reference yield:

D-xylose diethyl dithioacetal (13263-74-6) → 2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal (222408-75-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium p-toluenesylfonate / acetone

2: NaH / tetrahydrofuran / 0 °C

With pyridinium p-toluenesulfonate; sodium hydride; In tetrahydrofuran; acetone;

DOI:10.1080/07328309908543989

Reference yield: 87.0%

2,3-di-O-benzyl-4,5-O-isopropylidene-D-xylose diethyl dithioacetal (222408-75-5) → 2,3-di-O-benzyl-D-xylose diethyl dithioacetal (138535-84-9)

Guidance literature:

With acetic acid; In water; for 16h;

DOI:10.1080/07328309908543989

upstream raw materials:

4,5-O-isopropylidene-D-xylose diethyl dithioacetal

benzyl bromide

D-xylose diethyl dithioacetal

Downstream raw materials:

2,3-di-O-benzyl-D-xylose diethyl dithioacetal