(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

Base Information

Chemical Name:(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane
CAS No.:575465-48-4
Molecular Formula:C₂₃H₂₆N₂O₅
Molecular Weight:410.47
Hs Code.:

Synonyms:(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

Suppliers and Price of (4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

There total 1 articles about (4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 98-88-4
benzoyl chloride

: 575465-43-9
(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl]amino}-1,3-oxazolan-2-one

: 575465-48-4
(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; for 4h; Heating;
DOI:10.1021/ol034696n

Reference yield: 90.0%

: 575465-48-4
(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

: 575465-50-8
2-[(1R)-1-(phenylcarboxamido)propyl]-1,3-dioxolane

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; at 20 ℃; for 0.25h;
DOI:10.1021/ol034696n

Reference yield:

: 575465-48-4
(4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl](phenyl)carboxamido}-2-oxo-1,3-oxazolane

: 67942-91-0
(R)-2-(phenylcarboxamido)butanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / SmI₂; HMPA / tetrahydrofuran / 0.25 h / 20 °C

2: 94 percent / ozone / ethyl acetate / 0.12 h / -78 °C

3: 92 percent / LiOH*H₂O / dioxane; H₂O / 2.5 h / 0 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hydroxide; samarium diiodide; ozone; In tetrahydrofuran; 1,4-dioxane; water; ethyl acetate;
DOI:10.1021/ol034696n