C₃₂H₄₅ClFN₃O₄Si₂

Base Information

Chemical Name:C₃₂H₄₅ClFN₃O₄Si₂
CAS No.:1445379-90-7
Molecular Formula:C₃₂H₄₅ClFN₃O₄Si₂
Molecular Weight:646.349
Hs Code.:

C<sub>32</sub>H<sub>45</sub>ClFN<sub>3</sub>O<sub>4</sub>Si<sub>2</sub>

Synonyms:C₃₂H₄₅ClFN₃O₄Si₂

Suppliers and Price of C₃₂H₄₅ClFN₃O₄Si₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of C₃₂H₄₅ClFN₃O₄Si₂

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

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Technology Process of C₃₂H₄₅ClFN₃O₄Si₂

There total 11 articles about C₃₂H₄₅ClFN₃O₄Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

: 1445379-88-3
C₃₂H₄₄ClFN₂O₅Si₂

: 1445379-90-7
C₃₂H₄₅ClFN₃O₄Si₂

Guidance literature:: C₃₂H₄₄ClFN₂O₅Si₂; With dmap; Triphenylsilyl chloride; triethylamine; In acetonitrile; at 20 ℃; for 14h;

With ammonia; In tetrahydrofuran; acetonitrile; at 20 ℃; for 2h;

Reference yield:

: C₄₇H₆₆ClFN₂O₇SSi₂

: 1445379-90-7
C₃₂H₄₅ClFN₃O₄Si₂

Guidance literature:: With ammonium hydroxide; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1021/jm5017279

Reference yield:

: 1445379-59-8
2’-deoxy-2’-fluoro-3’-O-(tert-butyldimethylsilyl)uridine

: 1445379-90-7
C₃₂H₄₅ClFN₃O₄Si₂

Guidance literature:: Multi-step reaction with 6 steps

1.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 3 h / Reflux

2.1: sodium hydroxide / 1,4-dioxane; water / 2 h / 20 °C

2.2: 0.5 h / 20 °C / pH 7

3.1: pyridine / dichloromethane / 14 h / 0 - 20 °C

4.1: 1H-imidazole / dichloromethane / 14 h / 20 °C

4.2: 15 h / 20 °C

5.1: triphenylphosphine; tetrachloromethane / 0.67 h / 130 °C / Microwave irradiation; Inert atmosphere

6.1: Triphenylsilyl chloride; dmap; triethylamine / acetonitrile / 14 h / 20 °C

6.2: 2 h / 20 °C

With pyridine; 1H-imidazole; tetrachloromethane; dmap; Triphenylsilyl chloride; triethylamine; triphenylphosphine; sodium hydroxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In 1,4-dioxane; dichloromethane; water; acetonitrile;