(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

Base Information

Chemical Name:(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate
CAS No.:1003576-69-9
Molecular Formula:C₂₄H₂₃F₃N₄O₅
Molecular Weight:504.466
Hs Code.:

Synonyms:(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

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Chemical Property of (S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

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Technology Process of (S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

There total 2 articles about (S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1003576-68-8
(S)-methyl 3-amino-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

: 619-86-3
4-(ethoxy)benzoic acid

: 1003576-69-9
(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; for 24h;
DOI:10.1016/j.bmc.2010.01.067

Reference yield: 84.0%

: 1003576-69-9
(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

Guidance literature:

Reference yield: 74.0%

: 1003576-69-9
(S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate

: (S)-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}-1-(hydroxymethyl)ethyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide

Guidance literature:: (S)-methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}-N-{[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl}alaninate; With sodium tetrahydroborate; lithium chloride; In tetrahydrofuran; ethanol; at 18 - 25 ℃; for 18h;

With hydrogenchloride; In water; pH=2 - 3;