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619-86-3 Usage


4-Ethoxybenzoic acid is a white to light yellow crystal powder that serves as an important intermediate in the synthesis of various compounds and materials. It is known for its versatile chemical properties, which make it a valuable component in different industries.


Used in Liquid Crystals Industry:
4-Ethoxybenzoic acid is used as an intermediate for the production of liquid crystals, which are essential components in the manufacturing of display devices such as televisions, computer monitors, and smartphones. Its chemical properties contribute to the development of advanced liquid crystal materials with improved performance characteristics.
Used in Carbon Nanotube Thin Films:
4-Ethoxybenzoic acid is used as a precursor in the preparation of highly conducting and flexible few-walled carbon nanotube thin films. These films have potential applications in the development of advanced electronic devices, sensors, and energy storage systems due to their unique electrical and mechanical properties.

Flammability and Explosibility


Check Digit Verification of cas no

The CAS Registry Mumber 619-86-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 619-86:
83 % 10 = 3
So 619-86-3 is a valid CAS Registry Number.

619-86-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Detail
  • Alfa Aesar

  • (A12309)  4-Ethoxybenzoic acid, 98+%   

  • 619-86-3

  • 25g

  • 440.0CNY

  • Detail
  • Alfa Aesar

  • (A12309)  4-Ethoxybenzoic acid, 98+%   

  • 619-86-3

  • 100g

  • 1212.0CNY

  • Detail
  • Alfa Aesar

  • (A12309)  4-Ethoxybenzoic acid, 98+%   

  • 619-86-3

  • 500g

  • 3426.0CNY

  • Detail
  • Aldrich

  • (144959)  4-Ethoxybenzoicacid  99%

  • 619-86-3

  • 144959-25G

  • 456.30CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name 4-Ethoxybenzoic acid

1.2 Other means of identification

Product number -
Other names 4-ethoxy benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:619-86-3 SDS

619-86-3Relevant articles and documents

Synthesis and mesomorphic properties of bis ester derivatives of coumarin containing chalcone linkage

Shah, Priyanka,Soni, Rina,Soman, Shubhangi S

, (2021/05/04)

Bis ester derivatives of coumarin containing chalcone linkage with various terminal alkoxy groups were designed, synthesized and characterized. Compounds 11a-m were studied for their mesomorphic properties using polarizing optical microscope & differential scanning calorimetry and photophysical properties using UV-vis & fluorescence spectroscopy. In this particular homologous series, compounds having lower flexible alkoxy chains showed very good mesogenic property with nematic mesophase formation, while analogues with higher chains failed to show any liquid crystalline property. Compound 11a with methoxy group showed very good absorbance and fluorescence as compared to higher chain length analogues.

Novel ester derivative of cinnamates with different long alkoxy chain: synthesis, mesomorphic properties, biological evaluation

Bhalodiya, Pradip C.,Patel, Hemant N.,Parmar, Tejasvi H.,Sangani, Chetan B.,Rajani, Dhanji P.

, p. 1 - 25 (2021/07/07)

A novel series of liquid crystals involving cinnamate-based mesogenic units interlinked between aromatic ester and alkyl bromide were designed and synthesized. All target molecules were confirmed by IR, 1H NMR, 13C NMR, ESI-MS, and elemental analysis. The mesomorphic behavior of novel synthesized materials (P1–P18), (V1–V18), and (M1–M18) was investigated through a polarizing optical microscope, differential scanning calorimetry, and thermogravimetric analysis (TGA) analysis. The lower carbon chain substituted member showed nematic phase while compound possess higher carbon chain exhibited only SmC phase. Thermal stability is determined by TGA analysis. All the cinnamate derivatives were screened for their anti-microbial, anti-malarial, and anti-tuberculosis potency. Among them, most of the derivatives exhibited outstanding anti-bacterial and anti-tuberculosis activity. Some derivatives also exhibited potent anti-fungal activity.

Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease

Bai, Renren,Gu, Jinping,Guo, Jianan,Jiang, Xiaoying,Xie, Yuanyuan,Zhang, Changjun,Zhou, Tao

, p. 2045 - 2054 (2021/10/08)

A novel class of benzamide-hydroxypyridinone (HPO) derivatives were innovatively designed, synthesised, and biologically evaluated as potential multitargeting candidates for the treatment of Alzheimer's disease (AD) through pharmacophores-merged approaches based on lead compounds 18d, benzyloxy phenyl analogs, and deferiprone (DFP). These hybrids possessed potent Monoamine oxidase B (MAO-B) inhibition as well as excellent iron chelation, with pFe3+ values ranging from 18.13 to 19.39. Among all the compounds, 8g exhibited the most potent selective MAO-B inhibitor (IC50 = 68.4 nM, SI = 213). Moreover, 8g showed favourable pharmacokinetic properties and had great potential to penetrate the BBB in silico and PAMPA-BBB assay. Molecular modelling showed that 8g could adopt an extended conformation and have more enhanced interactions with MAO-B than 18d. In vitro and in vivo assays demonstrated that 8g remarkably resisted Aβ-induced oxidation and ameliorated cognitive impairment induced by scopolamine. Taken collectively, these results suggest that compound 8g is a potential multifunctional candidate for anti-AD treatment.

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