1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine

Base Information

• Chemical Name: 1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine
• CAS No.: 1421692-01-4
• Molecular Formula: C₁₉H₃₁NSi
• Molecular Weight: 301.547
• Mol file: 1421692-01-4.mol

Synonyms:1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine

Chemical Property of 1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine

There total 1 articles about 1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(4-isobutylphenyl)propanenitrile (58609-73-7) + tert-butyldimethylsilyl chloride (18162-48-6) → 1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine (1421692-01-4)

Guidance literature:

2-(4-isobutylphenyl)propanenitrile; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja312141b

Reference yield:

1-tert-butyl-N-(2-(4-isobutylphenyl)prop-1-enylidene)-1,1-dimethylsilanamine (1421692-01-4) → (S)-(-)-2-(4-isobutylphenyl)propionitrile (133868-69-6) + (2R)-2-[4-(2-methylpropyl)phenyl]propanenitrile (131319-89-6)

Guidance literature:

With (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; In methanol; toluene; pentane; at -78 - 20 ℃; for 12h; Overall yield = 86 %; Overall yield = 32 mg; enantioselective reaction;

DOI:10.1021/ja312141b

upstream raw materials:

2-(4-isobutylphenyl)propanenitrile

tert-butyldimethylsilyl chloride

Downstream raw materials:

(S)-(-)-2-(4-isobutylphenyl)propionitrile

(2R)-2-[4-(2-methylpropyl)phenyl]propanenitrile