p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Base Information

Chemical Name:p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide
CAS No.:159675-88-4
Molecular Formula:C₂₂H₂₃NO₅
Molecular Weight:381.428
Hs Code.:

Synonyms:p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Suppliers and Price of p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

There total 5 articles about p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 159675-87-3
p-Benzyloxycarbonyl-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

: 159675-88-4
p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Guidance literature:: With methanesulfonic acid; In various solvent(s); for 2h;
DOI:10.1021/jm00022a017

Reference yield:

: 78767-55-2
benzyl 4-formylbenzoate

: 159675-88-4
p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) sodium hydride / 1.) THF, 25 deg C, 30 min, 2.) THF, 25 deg C, 30 min

2: 84 percent / trifluoroacetic acid / various solvent(s) / 2 h

3: thionyl chloride / 1 h / Heating

4: pyridine / CH₂Cl₂ / 2 h / 25 °C

5: methanesulfonic acid / various solvent(s) / 2 h

With pyridine; thionyl chloride; methanesulfonic acid; sodium hydride; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00022a017

Reference yield:

: 159675-82-8
p-Benzyloxycarbonyl-α-methylcinnamic acid

: 159675-88-4
p-Carboxy-α-methylcinnamic acid N-ethoxycarbonylmethyl-N-phenylmethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 1 h / Heating

2: pyridine / CH₂Cl₂ / 2 h / 25 °C

3: methanesulfonic acid / various solvent(s) / 2 h

With pyridine; thionyl chloride; methanesulfonic acid; In dichloromethane;
DOI:10.1021/jm00022a017