Technology Process of C26H21N3
There total 3 articles about C26H21N3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(2,4,6-trimethylphenyl)-6-bromopyridine;
With
n-butyllithium;
In
diethyl ether; hexane;
at -78 - -40 ℃;
for 2.25h;
Inert atmosphere;
1,10-Phenanthroline;
In
diethyl ether; hexane;
at -40 - 20 ℃;
for 12h;
Inert atmosphere;
With
manganese(IV) oxide;
In
dichloromethane;
at 20 ℃;
for 12h;
DOI:10.1039/c4dt00849a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / methanol; tetrahydrofuran; water / 12 h / 90 °C
2.1: n-butyllithium / diethyl ether; hexane / 2.25 h / -78 - -40 °C / Inert atmosphere
2.2: 12 h / -40 - 20 °C / Inert atmosphere
2.3: 12 h / 20 °C
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; potassium carbonate;
In
tetrahydrofuran; methanol; diethyl ether; hexane; water;
1.1: |Suzuki Coupling;
DOI:10.1039/c4dt00849a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / methanol; tetrahydrofuran; water / 12 h / 90 °C
2.1: n-butyllithium / diethyl ether; hexane / 2.25 h / -78 - -40 °C / Inert atmosphere
2.2: 12 h / -40 - 20 °C / Inert atmosphere
2.3: 12 h / 20 °C
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; potassium carbonate;
In
tetrahydrofuran; methanol; diethyl ether; hexane; water;
1.1: |Suzuki Coupling;
DOI:10.1039/c4dt00849a
