Technology Process of 2-<(2,6-dichloro-3-methylphenyl)amino>benzenecarboximidic acid hydrazide
There total 4 articles about 2-<(2,6-dichloro-3-methylphenyl)amino>benzenecarboximidic acid hydrazide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
methanol;
for 5h;
Ambient temperature;
DOI:10.1021/jm00065a002
- Guidance literature:
-
Multi-step reaction with 4 steps
1: (COCl)2, DMF / CH2Cl2 / 1.) 0 deg C, 15 min, 2.) RT, 30 min
2: 29percent aq. NH3 / CH2Cl2; tetrahydrofuran / 1 h / Ambient temperature
3: 57 percent / Lawesson's reagent / tetrahydrofuran / 1.) RT, 3 d, 2.) reflux, 2 h
4: 68 percent / NH2NH2*H2O / methanol / 5 h / Ambient temperature
With
Lawessons reagent; ammonium hydroxide; oxalyl dichloride; hydrazine hydrate; N,N-dimethyl-formamide;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm00065a002
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 29percent aq. NH3 / CH2Cl2; tetrahydrofuran / 1 h / Ambient temperature
2: 57 percent / Lawesson's reagent / tetrahydrofuran / 1.) RT, 3 d, 2.) reflux, 2 h
3: 68 percent / NH2NH2*H2O / methanol / 5 h / Ambient temperature
With
Lawessons reagent; ammonium hydroxide; hydrazine hydrate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm00065a002
