C₄₄H₆₁N₅O₆

Base Information

• Chemical Name: C₄₄H₆₁N₅O₆
• CAS No.: 1009094-37-4
• Molecular Formula: C₄₄H₆₁N₅O₆
• Molecular Weight: 755.998
• Mol file: 1009094-37-4.mol

Synonyms:C₄₄H₆₁N₅O₆

Chemical Property of C₄₄H₆₁N₅O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₆₁N₅O₆

There total 10 articles about C₄₄H₆₁N₅O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

C33H45N3O7 (1009094-80-7) + N-[(2S)-2-amino-3-phenylpropyl]-N,N-dimethylamine (29802-26-4) → C44H61N5O6 (1009094-37-4)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

C15H18INO5 (874347-52-1) → C44H61N5O6 (1009094-37-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trimethylaluminum / hexane; dichloromethane / 0.25 h

1.2: 20 °C

1.3: 2 h

2.1: potassium acetate; caesium carbonate / dimethyl sulfoxide / 0.17 h

2.2: 10.5 h / 70 °C

3.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / dichloromethane / 2 h / 20 °C

With trimethylaluminum; potassium acetate; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In hexane; dichloromethane; dimethyl sulfoxide;

Reference yield:

C8H10INO2 (874347-50-9) → C44H61N5O6 (1009094-37-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: benzene / Heating / reflux

2.1: titanium(IV) isopropylate / toluene / 0.17 h / 120 °C / Microwave irradiation

2.2: 2 h

3.1: pyridine hydrogenfluoride / tetrahydrofuran; pyridine / 4 h / 20 °C

4.1: trimethylaluminum / hexane; dichloromethane / 0.25 h

4.2: 20 °C

4.3: 2 h

5.1: potassium acetate; caesium carbonate / dimethyl sulfoxide / 0.17 h

5.2: 10.5 h / 70 °C

6.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / dichloromethane / 2 h / 20 °C

With titanium(IV) isopropylate; trimethylaluminum; potassium acetate; caesium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; pyridine hydrogenfluoride; triethylamine; In tetrahydrofuran; pyridine; hexane; dichloromethane; dimethyl sulfoxide; toluene; benzene;

upstream raw materials:

C₃₃H₄₅N₃O₇

N-[(2S)-2-amino-3-phenylpropyl]-N,N-dimethylamine

C₈H₁₀INO₂

C₁₁H₁₂INO₄

Downstream raw materials:

C₄₈H₆₈N₆O₇

C₄₇H₆₆N₆O₇

C₄₆H₆₄N₆O₇

C₄₆H₆₃N₅O₈