29802-26-4

Basic information

• Product Name: S-N1,N1-DiMethyl-3-phenylpropane-1,2-diaMine 2HCl
• Synonyms: S-N1,N1-DiMethyl-3-phenylpropane-1,2-diaMine 2HCl;(S)-N1,N1-dimethyl-3-phenylpropane-1,2-diamine
• CAS NO: 29802-26-4
• Molecular Formula: C₁₁H₁₈N₂
• Molecular Weight: 251.1959
• Mol File: 29802-26-4.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: S-N1,N1-DiMethyl-3-phenylpropane-1,2-diaMine 2HCl(CAS DataBase Reference)
• NIST Chemistry Reference: S-N1,N1-DiMethyl-3-phenylpropane-1,2-diaMine 2HCl(29802-26-4)
• EPA Substance Registry System: S-N1,N1-DiMethyl-3-phenylpropane-1,2-diaMine 2HCl(29802-26-4)

Safety Data

• Hazardous Substances Data: 29802-26-4(Hazardous Substances Data)

Upstream product

• 29618-17-5 L-phenylalanine dimethylamide 
• 141403-49-8 (2S)-2-[N-(tert-butoxycarbonyl)amino]-3-phenyl-O-(4-methylphenylsulfonyl)propan-1-ol 
• 123665-42-9 (S)-2-Amino-N,N-dimethyl-3-phenyl-propionamide hydrochloride 
• 126301-19-7 (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 78800-68-7 (S)-tert-butyl 1-(dimethylamino)-1-oxo-3-phenylpropan-2-ylcarbamate 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 3182-95-4 L-Phenylalaninol 
• 340161-69-5 tert-butyl (S)-(1-(dimethylamino)-3-phenylpropan-2-yl)carbamate 

Downstream Products

• 259537-56-9 Benzyl 2-[3-[(3-[(tert-butoxycarbonyl)(methyl)amino]methylphenethyl)amino]-5-chloro-6-methyl-2-oxo-1(2 H)-pyrazinyl]acetate 
• 1048692-53-0 (S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(dimethylamino)-3-phenylpropan-2-yl)thiourea 
• 340161-69-5 tert-butyl (S)-(1-(dimethylamino)-3-phenylpropan-2-yl)carbamate 
• 943238-88-8 C₂₈H₃₃N₃O₃ 
• 1438263-84-3 (S)-N-(4-bromobenzyl)-N,N-dimethyl-2-(3-(4-nitrophenyl)thioureido)-3-phenylpropan-1-ammonium bromide 
• 1308662-08-9 2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester 
• 1308661-88-2 2-(3-{[(2,3-difluoro-6-methoxy-benzyl)-((S)-1-dimethylaminomethyl-2-phenyl-ethyl)-amino]-methyl}-benzyl)-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid((1S,2S,3S,5R)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)-amide 
• 1308661-80-4 2-(3-{[(6-chloro-2-fluoro-3-methoxy-benzyl)-((S)-1-dimethylaminomethyl-2-phenyl-ethyl)-amino]-methyl}-benzyl)-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ((1S,2S,3S,5R)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)-amide 
• 1308662-10-3 2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ((1S,2S,3S,5R)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)amide 
• 1308662-09-0 2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid 
• 1229900-78-0 (4S,5R,6R)-2-(acetoxymethyl)-6-(3-((S)-1-(dimethylamino)-3-phenylpropan-2-yl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 300547-19-7 1-[(1S)-1-Benzyl-2-(dimethylamino) ethyl]-3-(2-hydroxyethyl)-3-phenethyl urea 
• 1009091-91-1 C₄₈H₆₇N₅O₆ 
• 1009091-81-9 C₄₆H₆₅N₅O₆ 

Relevant articles and documents

PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS

The invention includes procedures for stereoselective β-arylation of carboxylic acids having a β-carbon atom. For example, stereoselective arylation procedures include the following reactions: (I)

Asymmetric hydroazidation of α-substituted vinyl ketones catalyzed by chiral primary amine

We report herein the first example of asymmetric hydroazidation of α-substituted vinyl ketones by using chiral primary amines as the catalysts. A simple chiral primary-tertiary diamine catalyst derived from L-phenylalanine was found to readily promote this aza-Michael addition reaction with enamine protonation as the key stereogenic step, thus enabling the effective synthesis of α-chiral β-azido ketones with good yields and moderate enantioselectivities.

Novel bifunctional thiourea-ammonium salt catalysts derived from amino acids: Application to highly enantio- and diastereoselective aza-Henry reaction

The development of new efficient and easily accessible catalysts has been one of the focuses in asymmetric phase-transfer catalysis. In this paper, a novel class of chiral bifunctional thiourea-ammonium phase-transfer catalysts were synthesized from commercially available α-amino acids. The structural modularity of these catalysts permits facile tunings to achieve optimum results, which was demonstrated in catalyzing the aza-Henry reaction with excellent enantioselectivities (up to 99.5% ee) and diastereoselectivities (up to >25:1 dr).