sulphamerazine

Base Information

• Chemical Name: sulphamerazine
• CAS No.: 599-84-8
• Molecular Formula: C₁₁H₁₂N₄O₂S
• Molecular Weight: 264.308
• Mol file: 599-84-8.mol

Synonyms:sulphamerazine

Chemical Property of sulphamerazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of sulphamerazine

There total 7 articles about sulphamerazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-2-methylpyrimidine (4994-86-9) → sulphamerazine (599-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃

2: aq. NaOH solution

With sodium hydroxide; potassium carbonate;

Reference yield:

4-chloro-2-methylpyrimidine (4994-86-9) + sulfanilamide (63-74-1) → sulphamerazine (599-84-8)

Guidance literature:

With potassium carbonate;

Reference yield:

4-nitro-benzenesulfonic acid-(2-methyl-pyrimidin-4-ylamide) (855230-90-9) → sulphamerazine (599-84-8)

Guidance literature:

With hydrogenchloride; iron;

DOI:10.1021/ja01255a030

upstream raw materials:

4-chloro-2-methylpyrimidine

sulfanilamide

4-nitro-benzenesulfonic acid-(2-methyl-pyrimidin-4-ylamide)

2-methyl-pyrimidin-4-ylamine

Downstream raw materials:

4-(2-Amino-4-phenyl-thiazol-5-ylazo)-N-(2-methyl-pyrimidin-4-yl)-benzenesulfonamide

4-[2-Amino-4-(4-ethoxy-phenyl)-thiazol-5-ylazo]-N-(2-methyl-pyrimidin-4-yl)-benzenesulfonamide

4-[2-Amino-4-(4-methoxy-phenyl)-thiazol-5-ylazo]-N-(2-methyl-pyrimidin-4-yl)-benzenesulfonamide

4-[2-Amino-4-(4-bromo-phenyl)-thiazol-5-ylazo]-N-(2-methyl-pyrimidin-4-yl)-benzenesulfonamide