1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

Base Information

Chemical Name:1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine
CAS No.:1416477-38-7
Molecular Formula:C₂₆H₂₇N₅O
Molecular Weight:425.533
Hs Code.:

Synonyms:1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

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Chemical Property of 1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

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Technology Process of 1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

There total 5 articles about 1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416477-59-2
tert-butyl {1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutyl}carbamate

: 1416477-38-7
1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃;

Reference yield:

: 16013-85-7,136901-10-5
2,6-dicholoro-3-nitropyridine

: 1416477-38-7
1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran / 20 °C

2: Heating

3: sodium dithionite / dimethyl sulfoxide; methanol / 100 °C

4: hydrogenchloride / 1,4-dioxane; methanol / 20 °C

With hydrogenchloride; sodium dithionite; In tetrahydrofuran; 1,4-dioxane; methanol; dimethyl sulfoxide;

Reference yield:

: 1416477-58-1
tert-butyl (1-{4-[(6-morpholin-4-yl-3-nitropyridin-2-yl)amino]phenyl}cyclobutyl)carbamate

: 1416477-38-7
1-[4-(5-morpholin-4-yl-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]cyclobutanamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium dithionite / dimethyl sulfoxide; methanol / 100 °C

2: hydrogenchloride / 1,4-dioxane; methanol / 20 °C

With hydrogenchloride; sodium dithionite; In 1,4-dioxane; methanol; dimethyl sulfoxide;