1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL

Base Information

Chemical Name:1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL
CAS No.:91021-63-5
Molecular Formula:C₂₈H₅₆NO₇P
Molecular Weight:549.729
Hs Code.:
Mol file:91021-63-5.mol

Synonyms:Pyrrolidinium,1-[7-(acetyloxy)-4-hydroxy-3,5,9-trioxa-4-phosphapentacos-1-yl]-1-methyl-,inner salt, P-oxide, (R)-; Pyrrolidinium,1-[7-(acetyloxy)-4-hydroxy-4-oxido-3,5,9-trioxa-4-phosphapentacos-1-yl]-1-methyl-,inner salt, (R)- (9CI)

Suppliers and Price of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Pyrrolidino PAF C-16 ≥98%
5mg
$ 176.00

Cayman Chemical
Pyrrolidino PAF C-16 ≥98%
10mg
$ 312.00

Cayman Chemical
Pyrrolidino PAF C-16 ≥98%
1mg
$ 39.00

ApexBio Technology
PyrrolidinoPAFC-16
10mg
$ 432.00

ApexBio Technology
PyrrolidinoPAFC-16
5mg
$ 244.00

AK Scientific
1-o-Hexadecyl-2-o-acetyl-Sn-glyceryl-3-phosphoryl-N-methyl-pyrrolidiniumethanol
1mg
$ 152.00

Total 6 raw suppliers

Chemical Property of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL

Chemical Property:

PSA：103.93000
LogP:7.18700
Solubility.:≤25mg/ml in PBS

Purity/Quality:

95% ^*data from raw suppliers

Pyrrolidino PAF C-16 ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Pyrrolidino PAF C-16 is a synthetic analog of PAF C-16. It is a potent mediator of PAF-like activities, including hypotension and platelet aggregation, where it is approximately 3-10 times more potent than PAF itself.

Technology Process of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL

There total 10 articles about 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL-N-METHYL-PYRROLIDINIUM ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 506-03-6
chimyl alcohol

: 91021-63-5
C₂₈H₅₆NO₇P

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / 4,4-dimethylaminopyridine / pyridine / 3 h / 100 °C

2: KH (22percent) / benzene / Ambient temperature

3: 92 percent / p-toluenesulfonic acid monohydrate / methanol / Heating

4: 1.) NEt₃; 2.) KCl (0.1N) / 1.) CHCl₃, room temp., 6h; 40 deg C, 12 h; 2.) 1 h

With dmap; potassium chloride; potassium hydride; toluene-4-sulfonic acid; triethylamine; In pyridine; methanol; benzene;
DOI:10.1248/cpb.33.572

Reference yield:

: 20779-14-0
methanesulfonic acid hexadecyl ester

: 91021-63-5
C₂₈H₅₆NO₇P

Guidance literature:: Multi-step reaction with 6 steps

1: 88 percent / KH (22percent) / benzene / 2 h / Heating

2: 91 percent / HCl (2N) / tetrahydrofuran / 3 h / Ambient temperature

3: Pb(OAc)4 / benzene / 2 h / Ambient temperature

4: NaBH₄ / methanol; tetrahydrofuran / Ambient temperature

5: 1.) NEt₃; 2.) KCl (0.1N) / 1.) CHCl₃, room temp., 6h; 40 deg C, 12 h; 2.) 1 h

With lead(IV) acetate; hydrogenchloride; sodium tetrahydroborate; potassium chloride; potassium hydride; triethylamine; In tetrahydrofuran; methanol; benzene;
DOI:10.1248/cpb.33.572

Reference yield:

: 92471-46-0
(R)-3-(1-hexadecyloxy)-1-(trityloxy)propan-2-ol

: 91021-63-5
C₂₈H₅₆NO₇P

Guidance literature:: Multi-step reaction with 4 steps

1: KH (22percent) / benzene / Ambient temperature

2: 92 percent / p-toluenesulfonic acid monohydrate / methanol / Heating

3: 1.) NEt₃; 2.) KCl (0.1N) / 1.) CHCl₃, room temp., 6h; 40 deg C, 12 h; 2.) 1 h

With potassium chloride; potassium hydride; toluene-4-sulfonic acid; triethylamine; In methanol; benzene;
DOI:10.1248/cpb.33.572