4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine

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Chemical Name:4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine
CAS No.:1159184-14-1
Molecular Formula:C₂₁H₂₄ClN₆O₈P
Molecular Weight:554.884
Hs Code.:

Synonyms:4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine

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Chemical Property of 4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine

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Technology Process of 4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine

There total 1 articles about 4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 690270-37-2
(3aR,4R,6R,6aS)-4-amino-1-(6-azido-6-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrimidin-2-one

: 693223-08-4
(4S)-(-)-trans-2-(4-nitrophenoxy)-2-oxo-4-(3-chlorophenyl)-1,3,2-dioxaphosphorinane

: 1159184-14-1
4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine

Guidance literature:: (3aR,4R,6R,6aS)-4-amino-1-(6-azido-6-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrimidin-2-one; With tert-butylmagnesium chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

(4S)-(-)-trans-2-(4-nitrophenoxy)-2-oxo-4-(3-chlorophenyl)-1,3,2-dioxaphosphorinane; In tetrahydrofuran; at 20 ℃; for 18h;