693223-08-4

Upstream product

• 99-02-5 3'-Chloroacetophenone 
• 33167-21-4 3-(3-chloro-phenyl)-3-oxo-propionic acid ethyl ester 
• 100-02-7 4-nitro-phenol 
• 777-52-6 1-dichlorophosphoryloxy-4-nitro-benzene 
• 625095-57-0 (S)-(-)-1-(3-Chlorophenyl)-1,3-propanediol 
• 804560-96-1 (+/-)-1-(1,3-bistrimethylsilyloxypropyl)-3-chlorobenzene 
• 625095-56-9 (S)-(-)-(3-chlorophenyl)-3-hydroxypropionic acid 
• 587-04-2 m-Chlorobenzaldehyde 
• 13422-80-5 3-(3-chlorophenyl)-3-oxopropanoic acid 
• 51699-40-2 3-(3-chlorophenyl)-3-hydroxypropionic acid ethyl ester 
• 51699-45-7 (S)-(-)-1-(3'-Chlorophenyl)-1,3-Propanediol 

Downstream Products

• 951663-21-1 C₂₃H₂₇ClN₅O₇P 
• 1159184-14-1 4'-azido-cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2',3'-O-isopropylidenylcytidine 
• 862189-29-5 cis-5'-O-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl]-2'-C-methyladenosine 
• 804561-62-4 2',3'-di-O-tert-butyldimethylsilyl-5'-O-cis-[4-(S)-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphoshorinan-2-yl]cytosine-1-β-D-arabinofuranoside 

Relevant academic research and scientific papers

Design, Synthesis, and Sustained-Release Property of 1,3-Cyclic Propanyl Phosphate Ester of 18β-Glycyrrhetinic Acid

A new class of potential prodrugs, 1,3-cyclic propanyl phosphate esters of 18β-glycyrrhetic acid, was designed and synthesized through the key reaction of 18β-glycyrrhetic acid with 1,3-cyclic propanyl phosphate ester catalysed by lithium diisopropylamide

NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES

Novel 2'-C-methyl nucleoside 5 '-monophosphate and 4'-C-methyl nucleoside 5'- monophosphate derivatives, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral inf

Novel 2'-C-methyl nucleoside derivatives

Compounds of Formula I, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described:

Design, Synthesis, and Characterization of a Series of Cytochrome P 450 3A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver

A new class of phosphate and phosphonate prodrugs, called HepDirect prodrugs, is described that combines properties of rapid liver cleavage with high plasma and tissue stability to achieve increased drug levels in the liver. The prodrugs are substituted c