2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine

Base Information

• Chemical Name: 2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine
• CAS No.: 117039-92-6
• Molecular Formula: C₁₇H₂₀ClN₅O₂
• Molecular Weight: 361.831
• Mol file: 117039-92-6.mol

Synonyms:2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine

Chemical Property of 2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine

There total 1 articles about 2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-6-chloropurin (10310-21-1) + 1-(benzyloxy)-2(S)-(chloromethoxy)butane (117039-91-5) → 2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine (117039-92-6)

Guidance literature:

With ammonium sulfate; mercury(II) cyanide; 1,1,1,3,3,3-hexamethyl-disilazane; Yield given. Multistep reaction; 1) reflux, overnight, 2) benzene, reflux, 3 h;

DOI:10.1021/jm00121a016

Reference yield: 50.0%

2-amino-6-chloro-9-<<1-(benzyloxy)-2(S)-butoxy>methyl>purine (117039-92-6) → 9-<<1-(benzyloxy)-2(S)-butoxy>methyl>guanine (117067-41-1)

Guidance literature:

With sodium hydroxide; In methanol; water; for 1.5h; Heating;

DOI:10.1021/jm00121a016

upstream raw materials:

2-Amino-6-chloropurin

1-(benzyloxy)-2(S)-(chloromethoxy)butane

Downstream raw materials:

9-<<1-(benzyloxy)-2(S)-butoxy>methyl>guanine