(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Base Information

Chemical Name:(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester
CAS No.:177341-34-3
Molecular Formula:C₁₇H₂₁NO₇
Molecular Weight:351.356
Hs Code.:

Synonyms:(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Suppliers and Price of (2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

There total 3 articles about (2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 26784-23-6
cis,cis-2,6-bis(methoxycarbonyl)-4-hydroxypiperidine

: 177341-34-3
(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; water; for 4h; Ambient temperature;
DOI:10.1021/jo9519569

Reference yield:

: 138-60-3
chelidamic acid

: 177341-34-3
(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 2,2-dimethoxypropane, HCl / 1.) reflux, 4 h, 2.) room temperature, overnight

2: 7.347 g / hydrogen / rhodium on alumina / H₂O / 15 h / 775.7 Torr / Ambient temperature

3: 90 percent / NaHCO₃ / CH₂Cl₂; H₂O / 4 h / Ambient temperature

With hydrogenchloride; hydrogen; sodium hydrogencarbonate; 2,2-dimethoxy-propane; Rh/Al₂O₃; In dichloromethane; water;
DOI:10.1021/jo9519569

Reference yield:

: 4-Oxo-1,4-dihydro-pyridine-2,6-dicarboxylic acid dimethyl ester; hydrochloride

: 177341-34-3
(2S,4S,6R)-4-Hydroxy-piperidine-1,2,6-tricarboxylic acid benzyl ester dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 7.347 g / hydrogen / rhodium on alumina / H₂O / 15 h / 775.7 Torr / Ambient temperature

2: 90 percent / NaHCO₃ / CH₂Cl₂; H₂O / 4 h / Ambient temperature

With hydrogen; sodium hydrogencarbonate; Rh/Al₂O₃; In dichloromethane; water;
DOI:10.1021/jo9519569