138-60-3

Usage

Uses

Used in Analytical Chemistry:
Chelidamic acid is used as a complexing additive in high-performance chelation ion chromatography (HPCIC) for the speciation of iron. Its ability to form complexes with iron ions allows for the efficient separation and identification of different iron species in various samples.
Used in the Synthesis of Lanthanoid Hybrid Compounds:
Chelidamic acid is used as an organic ligand for the synthesis of polyoxometalate (POM)-based lanthanoid hybrid compounds. These compounds have potential applications in areas such as catalysis, magnetism, and electronics due to their unique structural and electronic properties. The use of Chelidamic acid as a ligand contributes to the formation of these complex structures and enhances their performance in various applications.

Biochem/physiol Actions

Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.

InChI:InChI=1/C7H5NO5/c9-3-1-4(6(10)11)8-5(2-3)7(12)13/h1-2H,(H,8,9)(H,10,11)(H,12,13)/p-2

Upstream product

• 99-32-1 chelidonic acid 

Downstream Products

• 99097-41-3 dibenzyl 4-(benzyloxy)-2,6-pyridinedicarboxylate 
• 68631-52-7 4-hydroxypyridine-2,6-dicarboxylic acid diethylester 
• 19872-91-4 dimethyl 4-hydroxypyridine-2,6-dicarboxylate 
• 289038-69-3 4-oxo-1,4-dihydro-pyridine-2,6-dicarboxylic acid dibenzyl ester 
• 696609-70-8 dibenzyl 4-pentyloxycarbonylmethoxypyridine-2,6-dicarboxylate 
• 696609-86-6 bis-pentafluorophenyl 4-pentyloxycarbonylmethoxypyridine-2,6-dicarboxylate 
• 3648-29-1 4-(dimethylamino)pyridine-2,6-dicarboxylic acid 
• 308245-25-2 4-chloro-2,6-bis[((2-(1S,2S)-1-(4-methylthiophenyl)-1,3-propanediylbisacetate)carbamoylphenyl)carbamoyl]pyridine 
• 308245-26-3 4-amino-2,6-bis[((2-(1S,2S)-1-(4-methylthiophenyl)-1,3-propanediyl-bisacetate)carbamoylphenyl)carbamoyl]pyridine 
• 17792-32-4 2,6-Dicarbamoyl-4-phenoxypyridin 
• 195967-10-3 1,1'-(4-chloropyridine-2,6-diyl)diethanone 
• 259184-75-3 C₄₅H₆₂ClN₃O₆ 
• 112776-83-7 diethyl 4-bromo-2,6-pyridinedicarboxylate 
• 144433-70-5 N-carbobenzoxy-cis-2,6-bis(hydroxymethyl)piperidine 

Related news

Syntheses, crystal structures, and magnetic and luminescent properties of a series of lanthanide coordination polymers with Chelidamic acid (cas 138-60-3) ligand09/30/2019

A series of lanthanide(III) complexes with chelidamic acid ligand, [Ln(C 7 H 2 NO 5 )·3H 2 O] n ·nH 2 O (Ln=La (1), Y (2), Sm (3), and Nd (4)), [Gd 2 (C 7 H 2 NO 5 ) 3 ·4H 2 O] n ·2nH ...detailed

Synthesis, characterization, spectroscopic, crystal structures and solution studies of two coordination compounds of zinc(II) and iron(III) based on Chelidamic acid (cas 138-60-3) and acridine09/29/2019

Two new proton transfer compounds, (acrH) 2 [Zn(hypydc) 2 ]·10H 2 O 1 and (acrH)[Fe(hypydc) 2 ]·4.5H 2 O 2 [where hypydcH 2 =4-hydroxypyridine-2,6-dicarboxylic acid (chelidamic acid) and acr=acridine] have been synthesized and characterized by el...detailed

Relevant academic research and scientific papers

Separation of Am (III) by solvent extraction using water-soluble H4tpaen derivatives

The water-soluble ligand N,N,N′,N′-tetrakis[(6-carboxypyridin-2-yl)methyl]ethylenediamine (H4tpaen) and its derivatives were synthesized and evaluated for Am/Cm separation by solvent extraction. In this context, different ligands were studied for their possible use as selective back-extraction agents of actinides, especially americium, from an organic TPH phase. The solvent consisted of different extractants mixtures (DMDOHEMA/HDEHP or TODGA/TBP systems) and was preliminarily loaded with trivalent lanthanide and actinide cations. The aim of these new water-soluble agents was to strip americium or curium in an aqueous acidic phase in order to perform their mutual separation while maintaining other cations in the organic phase. A specific ligand bearing n-alkoxy groups connected to the pyridyl rings of H4tpaen showed water solubility slightly enhanced associated with efficient back-extraction properties with the possibility to perform simultaneously inter-group separation of Am (III) from Eu (III), and intra-group separation of Am(III) from Cm(III).

The assembly of "s3N"-ligands decorated with an azo-dye as potential sensors for heavy metal ions

An "S3N-ligand azo-dye" conjugate has been synthesised with a view to the development of a sensor for heavy metal ions. Complexation of this system with Ag(i), Hg(ii) and Cu(ii) salts has been investigated and an X-ray structure has been obtained for a Hg(ii) complex. Complexation of the conjugated dye to these metals results in a bathochromic shift in the absorption maximum of the azo dye, an effect which is most pronounced for Cu(ii).

The Synthesis of Group 10 and 11 Metal Complexes of 3,6,9-Trithia-1-(2,6)-pyridinacyclodecaphane and Their Use in A3-Coupling Reactions

The reaction between 3,6,9-trithia-1(2,6)-pyridinacyclodecaphane and representative group 10 and 11 metal salts [Cu(NO3)2, NiCl2 or Ag(CF3CO2)] afforded 1:1 complexes, which in the case of CuII and AgI were characterised by single-crystal X-ray crystallography. The catalytic activity of these complexes in A3-coupling reactions between aldehydes, terminal alkynes and amines was assessed in both protic (water) and aprotic (toluene) media. These A3-reactions prove to be more efficient, proceed with lower catalyst loadings and with faster reaction rates, when conducted in a focused microwave reactor as compared to the same reactions promoted by standard, thermal, modes of activation.

A new efficient method for the preparation of 2,6-pyridinedimethyl ditosylates from dimethyl 2,6-pyridinedicarboxylates

We report here an efficient method for the preparation of 2,6- pyridinedimethyl ditosylate and four of its 4-substituted derivatives, two of them have not been reported in the literature. We also describe here a modification of the reported synthesis for chelidonic and chelidamic acids with improved yields and higher purity.

The Reactions of Arylamines with Chelidonic Acid

Depending on the conditions, and the basicity of the amine, arylamines react with chelidonic acid to yield five different types of product: salts, N-arylchelidamic acids, N-aryl-4-pyridone-2-carboxylic acids, N-aryl-4-pyridones, or chelidamic acid itself.