Technology Process of N,N-dibenzyl-2-cyano-2-diazoacetamide
There total 2 articles about N,N-dibenzyl-2-cyano-2-diazoacetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 3 h / 20 °C
1.2: 1 h / 0 - 20 °C
2.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 1 h / 0 - 20 °C
3.1: sodium azide; trifluoromethylsulfonic anhydride; triethylamine / dichloromethane; water / 2 h / 20 °C / 6000.6 Torr
With
dmap; sodium azide; trifluoromethylsulfonic anhydride; triethylamine; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane; water;
3.1: |Regitz Diazo Transfer;
DOI:10.1021/acs.joc.1c01310
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 3 h / 20 °C
1.2: 1 h / 0 - 20 °C
2.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 1 h / 0 - 20 °C
3.1: sodium azide; trifluoromethylsulfonic anhydride; triethylamine / dichloromethane; water / 2 h / 20 °C / 6000.6 Torr
With
dmap; sodium azide; trifluoromethylsulfonic anhydride; triethylamine; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane; water;
3.1: |Regitz Diazo Transfer;
DOI:10.1021/acs.joc.1c01310
- Guidance literature:
-
With
copper acetylacetonate;
In
1,2-dichloro-ethane;
for 0.5h;
Reagent/catalyst;
Solvent;
chemospecific reaction;
Reflux;
Inert atmosphere;
Green chemistry;
DOI:10.1002/cctc.201400014
