5-Methoxy-4-methylbenzimidazole

Base Information

Chemical Name:5-Methoxy-4-methylbenzimidazole
CAS No.:90868-11-4
Molecular Formula:C₉H₁₀N₂O
Molecular Weight:162.191
Hs Code.:
DSSTox Substance ID:DTXSID001292331
Mol file:90868-11-4.mol

Synonyms:5-Methoxy-4-methylbenzimidazole;90868-11-4;5-methoxy-4-methyl-1H-benzimidazole;1H-Benzimidazole,5-methoxy-4-methyl-(9CI);MFCD18807682;5-methoxy-4-methyl-1H-1,3-benzodiazole;SCHEMBL7343538;AATWEYWNIHXOFA-UHFFFAOYSA-N;DTXSID001292331;AC2081;6-Methoxy-7-methyl-1H-benzimidazole;AKOS027257065;CS-12048;DA-40644;SY036281;A916391

Suppliers and Price of 5-Methoxy-4-methylbenzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Methoxy-4-methylbenzimidazole
100mg
$ 175.00

Crysdot
5-Methoxy-4-methylbenzimidazole 95+%
5g
$ 1037.00

Crysdot
5-Methoxy-4-methylbenzimidazole 95+%
1g
$ 329.00

Chemenu
5-Methoxy-4-methylbenzimidazole 95%
1g
$ 310.00

Chemenu
5-Methoxy-4-methylbenzimidazole 95%
5g
$ 977.00

Alichem
5-Methoxy-4-methylbenzimidazole
1g
$ 345.28

Alichem
5-Methoxy-4-methylbenzimidazole
5g
$ 1118.15

AK Scientific
5-Methoxy-4-methylbenzimidazole
5g
$ 1545.00

Total 4 raw suppliers

Chemical Property of 5-Methoxy-4-methylbenzimidazole

Chemical Property:

Boiling Point:386.3±22.0 °C(Predicted)
PKA:13.68±0.30(Predicted)
PSA：37.91000
Density:1.198±0.06 g/cm3(Predicted)
LogP:1.87990
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

5-Methoxy-4-methylbenzimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC2=C1N=CN2)OC

Technology Process of 5-Methoxy-4-methylbenzimidazole

There total 5 articles about 5-Methoxy-4-methylbenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 97433-22-2
4-methoxy-3-methyl-1,2-benzenediamine

: 149-73-5
trimethyl orthoformate

: 90868-11-4
5-methoxy-4-methyl-1H-benzo[d]imidazole

Guidance literature:: With hydrogenchloride; at 80 ℃; for 1h;
DOI:10.1021/jacs.1c05531

Reference yield:

: 97433-22-2
4-methoxy-3-methyl-1,2-benzenediamine

: 90868-11-4
5-methoxy-4-methyl-1H-benzo[d]imidazole

Guidance literature:: With formic acid;

Reference yield:

: 19500-02-8
2-methyl-3-methoxyaniline

: 90868-11-4
5-methoxy-4-methyl-1H-benzo[d]imidazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: chlorosulfonic acid; triethylamine / dichloromethane / 1 h / 0 - 20 °C

2.1: iron(II) bromide; O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate / 4 h / 30 °C

2.2: 1 h / 20 °C

3.1: hydrogenchloride / 1 h / 80 °C

With hydrogenchloride; chlorosulfonic acid; O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; triethylamine; iron(II) bromide; In dichloromethane;
DOI:10.1021/jacs.1c05531