2,4,4-trimethyl-1-pentyl hypophosphorous acid

Base Information

• Chemical Name: 2,4,4-trimethyl-1-pentyl hypophosphorous acid
• CAS No.: 144900-28-7
• Molecular Formula: C₈H₁₉O₂P
• Molecular Weight: 178.211
• Mol file: 144900-28-7.mol

Synonyms:2,4,4-trimethyl-1-pentyl hypophosphorous acid

Chemical Property of 2,4,4-trimethyl-1-pentyl hypophosphorous acid

Chemical Property:

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,4-trimethyl-1-pentyl hypophosphorous acid

There total 1 articles about 2,4,4-trimethyl-1-pentyl hypophosphorous acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.9%

2,4,4-trimethyl-1-pentene (107-39-1) + 2,4,4-trimethylpent-2-ene (107-40-4) → bis(2,4,4-trimethylpentyl)phosphinic acid (83411-71-6) + 2,4,4-trimethyl-1-pentyl hypophosphorous acid (144900-28-7)

Guidance literature:

With sodium hypophosphite hydrate; di-tert-butyl peroxide; acetic acid; at 135 ℃; for 30h;

Reference yield:

3,5-di-tert-butyl-4-hydroxy benzyl chloride (955-01-1) + 2,4,4-trimethyl-1-pentyl hypophosphorous acid (144900-28-7) → C26H49O3PSi

Guidance literature:

2,4,4-trimethyl-1-pentyl hypophosphorous acid; With N,O-bis-(trimethylsilyl)-acetamide; In dichloromethane; for 4h; Reflux;

3,5-di-tert-butyl-4-hydroxy benzyl chloride; In dichloromethane; for 3h; Reflux;

Reference yield:

2,4,4-trimethyl-1-pentyl hypophosphorous acid (144900-28-7) → (3,5-di-tert-butyl-4-hydroxy-benzyl)-(2,4,4-trimethylpentyl)phosphinic acid (1189189-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 4 h / Reflux

1.2: 3 h / Reflux

2.1: hydrogenchloride / methanol; water

With hydrogenchloride; N,O-bis-(trimethylsilyl)-acetamide; In methanol; dichloromethane; water;

upstream raw materials:

2,4,4-trimethyl-1-pentene

2,4,4-trimethylpent-2-ene

Downstream raw materials:

(3,5-di-tert-butyl-4-hydroxy-benzyl)-(2,4,4-trimethylpentyl)phosphinic acid