(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

Base Information

Chemical Name:(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide
CAS No.:118331-98-9
Molecular Formula:C₂₀H₂₇N₃OS*ClH
Molecular Weight:393.981
Hs Code.:

Synonyms:(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

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Chemical Property of (1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

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Technology Process of (1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

There total 4 articles about (1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 118331-98-9
(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: DCC

2: H₂ / 10percent Pd/C / 2585.7 Torr

3: sat. NaHCO₃ / CHCl₃

With hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; palladium on activated charcoal; In chloroform;
DOI:10.1021/jm00122a001

Reference yield:

: 67347-43-7
(1R,2R)-(-)-trans-2-pyrrolidinyl-N-methylcyclohexylamine

: 118331-98-9
(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: DCC

2: H₂ / 10percent Pd/C / 2585.7 Torr

3: sat. NaHCO₃ / CHCl₃

With hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; palladium on activated charcoal; In chloroform;
DOI:10.1021/jm00122a001

Reference yield:

: 118170-32-4
(1R,2R)-trans-2-nitro-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

: 118331-98-9
(1R,2R)-trans-2-isothiocyanato-N-methyl-N-<2-(1-pyrrolidinyl)cyclohexyl>benzeneacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / 2585.7 Torr

2: sat. NaHCO₃ / CHCl₃

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In chloroform;
DOI:10.1021/jm00122a001