Technology Process of 4-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranos-1-ylmethyl)-3-benzyloxybenzoic ethyl ester
There total 9 articles about 4-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranos-1-ylmethyl)-3-benzyloxybenzoic ethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: 91 percent / tetrahydrofuran / 2 h / -78 °C
2.1: 78 percent / Et3SiH; BF3*OEt2 / CH2Cl2 / 12 h / -78 °C
3.1: ozone / CH2Cl2; methanol / -78 °C
3.2: PPh3
4.1: 22.9 g / toluene / 2 h / Heating
5.1: 88 percent / DIBAL / toluene / -78 - 25 °C
6.1: MnO2 / CH2Cl2 / 3 h / Heating
7.1: 13.3 g / CH2Cl2 / 3 h / Heating
8.1: 65 percent / ethyl chloroformate; Et3N / tetrahydrofuran / 0.5 h / 20 °C
9.1: 87 percent / K2CO3 / acetone / 12 h
With
triethylsilane; manganese(IV) oxide; boron trifluoride diethyl etherate; chloroformic acid ethyl ester; diisobutylaluminium hydride; potassium carbonate; ozone; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; acetone; toluene;
4.1: Wittig reaction / 7.1: Wittig reaction;
DOI:10.1002/1521-3765(20020415)8:8<1872::AID-CHEM1872>3.0.CO;2-A
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: Jones reagent / acetone
2.1: 91 percent / tetrahydrofuran / 2 h / -78 °C
3.1: 78 percent / Et3SiH; BF3*OEt2 / CH2Cl2 / 12 h / -78 °C
4.1: ozone / CH2Cl2; methanol / -78 °C
4.2: PPh3
5.1: 22.9 g / toluene / 2 h / Heating
6.1: 88 percent / DIBAL / toluene / -78 - 25 °C
7.1: MnO2 / CH2Cl2 / 3 h / Heating
8.1: 13.3 g / CH2Cl2 / 3 h / Heating
9.1: 65 percent / ethyl chloroformate; Et3N / tetrahydrofuran / 0.5 h / 20 °C
10.1: 87 percent / K2CO3 / acetone / 12 h
With
triethylsilane; manganese(IV) oxide; jones reagent; boron trifluoride diethyl etherate; chloroformic acid ethyl ester; diisobutylaluminium hydride; potassium carbonate; ozone; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; acetone; toluene;
5.1: Wittig reaction / 8.1: Wittig reaction;
DOI:10.1002/1521-3765(20020415)8:8<1872::AID-CHEM1872>3.0.CO;2-A
