Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-

Base Information

Chemical Name:Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-
CAS No.:90749-80-7
Molecular Formula:C₁₄H₂₄N₄O₄
Molecular Weight:312.369
Hs Code.:
Mol file:90749-80-7.mol

Synonyms:Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-

Suppliers and Price of Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-

Chemical Property:

PSA：108.35000
LogP:0.80450

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy-

There total 2 articles about Butanamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 29006-02-8
4-methoxybutyric acid

: 78033-18-8
5,6-diamino-1-isobutyl-3-methyl-1H-pyrimidine-2,4-dione

: 90749-80-7
N-(6-Amino-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-methoxy-butyramide

Guidance literature:: 1.) 100 deg C, 4 h; 2.) 20 deg C, 20 h;
DOI:10.1016/0223-5234(87)90056-0

Reference yield:

: 54052-67-4
1-isobutyl-3-methyl-5-nitroso-6-amino uracil

: 90749-80-7
N-(6-Amino-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-methoxy-butyramide

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / H₂ / Raney-NiW-2 / methanol / 4 h / 5320 Torr

2: 85 percent / 1.) 100 deg C, 4 h; 2.) 20 deg C, 20 h

With hydrogen; Raney-NiW-2; In methanol;
DOI:10.1016/0223-5234(87)90056-0

Reference yield:

: 90749-80-7
N-(6-Amino-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-methoxy-butyramide

: 90749-55-6
8-[3-(4-Benzhydryloxy-piperidin-1-yl)-propyl]-3-isobutyl-1,7-dimethyl-3,7-dihydro-purine-2,6-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / 12N NaOH / H₂O / 2 h / 100 °C

2: 89 percent / K₂CO₃ / dimethylformamide / 3 h / 50 °C

3: 67 percent / 48percent HBr, HBr (gas) / 20 h / Heating

4: 77 percent / methanol / Heating

With sodium hydroxide; hydrogen bromide; potassium carbonate; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(87)90056-0