1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene

Base Information

• Chemical Name: 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene
• CAS No.: 181058-10-6
• Molecular Formula: C₁₈H₃₃N₃
• Molecular Weight: 291.48
• Mol file: 181058-10-6.mol

Synonyms:1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene

Chemical Property of 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene

There total 4 articles about 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,3,5-tris(cyanomethyl)-2,4,6-triethylbenzene (181058-09-3) → 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene (181058-10-6)

Guidance literature:

With ammonia; hydrogen; Raney-Co; In methanol; water; at 20 ℃; for 16h; under 6000.48 Torr;

DOI:10.1039/b613254e

Reference yield:

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene (181058-08-2) → 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene (181058-10-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / dimethylsulfoxide / 20 - 50 °C

2: 53 percent / LiAlH₄; AlCl₃ / tetrahydrofuran / 3 h / Heating

With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; dimethyl sulfoxide;

DOI:10.1021/ja068754m

Reference yield:

1,3,5-triethylbenzene (102-25-0) → 1,3,5-tris(2'-aminoethyl)-2,4,6-triethylbenzene (181058-10-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 77 percent / SnCl₄ / CH₂Cl₂ / 3 h / 0 - 5 °C

2: 88 percent / H₂O; acetone / 15 h / Heating

3: 63 percent / BH₃*THF / tetrahydrofuran / 40 h / Heating

With borane-THF; tin(IV) chloride; In tetrahydrofuran; dichloromethane; water; acetone; 1: procedure of Gambarova;

DOI:10.1016/S0040-4020(01)00248-4

upstream raw materials:

1,3,5-tris(cyanomethyl)-2,4,6-triethylbenzene

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene

1,3,5-triethylbenzene

1,3,5-tris(chloromethyl)-2,4,6-triethylbenzene

Downstream raw materials:

C₄₅H₇₈N₆O₉