benzamide, 3,5-dibromo-2-methoxy-

Base Information

• Chemical Name: benzamide, 3,5-dibromo-2-methoxy-
• CAS No.: 90050-67-2
• Molecular Formula: C₈H₇Br₂NO₂
• Molecular Weight: 308.957
• Mol file: 90050-67-2.mol

Synonyms:3,5-dibromo-2-methoxybenzamide

Chemical Property of benzamide, 3,5-dibromo-2-methoxy-

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3,5-Dibromo-2-methoxybenzamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzamide, 3,5-dibromo-2-methoxy-

There total 2 articles about benzamide, 3,5-dibromo-2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3,5-dibromo-2-methoxyphenylzinc bromide (1239315-84-4) + Trichloroacetyl isocyanate (3019-71-4) → 3,5-dibromo-2-methoxybenzamide (90050-67-2)

Guidance literature:

3,5-dibromo-2-methoxyphenylzinc bromide; Trichloroacetyl isocyanate; In tetrahydrofuran; at -20 - 25 ℃; Inert atmosphere;

With methanol; potassium carbonate; In tetrahydrofuran; at 25 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol101469f

Reference yield:

3,5-dibromosalicylic acid (3147-55-5) → 3,5-dibromo-2-methoxybenzamide (90050-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH solution

2: phosphorus (V)-chloride / Behandeln des Reaktionsgemisches mit wss. Ammoniak

With sodium hydroxide; phosphorus pentachloride;

DOI:10.1007/BF03263078

Reference yield:

3,5-dibromo-2-methoxybenzamide (90050-67-2) + chloral (75-87-6) → 3,5-dibromo-2-methoxy-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide) (860522-99-2)

Guidance literature:

at 140 - 150 ℃;

upstream raw materials:

3,5-dibromosalicylic acid

3,5-dibromo-2-methoxyphenylzinc bromide

Trichloroacetyl isocyanate

Downstream raw materials:

3,5-dibromo-2-methoxy-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide)