Ethyl 2-fluoro-4-vinylbenzoate

Base Information

Chemical Name:Ethyl 2-fluoro-4-vinylbenzoate
CAS No.:1416979-62-8
Molecular Formula:C₁₁H₁₁FO₂
Molecular Weight:194.206
Hs Code.:

Synonyms:Ethyl 2-fluoro-4-vinylbenzoate

Suppliers and Price of Ethyl 2-fluoro-4-vinylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Ethyl 2-fluoro-4-vinylbenzoate

Chemical Property:

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Technology Process of Ethyl 2-fluoro-4-vinylbenzoate

There total 3 articles about Ethyl 2-fluoro-4-vinylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 474709-71-2
4-bromo-2-fluorobenzoic acid ethyl ester

: potassium vinyltrifluoroborate

: 1416979-62-8
Ethyl 2-fluoro-4-vinylbenzoate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate; In tetrahydrofuran; water; at 85 ℃; for 22h; Sealed tube; Inert atmosphere;
DOI:10.1016/j.tet.2021.132535

Reference yield: 50.0%

: 1416979-62-8
Ethyl 2-fluoro-4-vinylbenzoate

Guidance literature:

Reference yield:

: 112704-79-7
2-fluoro-4-bromobenzoic acid

: 1416979-62-8
Ethyl 2-fluoro-4-vinylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 20 - 80 °C

2: caesium carbonate; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran; water / 22 h / 85 °C / Sealed tube; Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; sulfuric acid; caesium carbonate; In tetrahydrofuran; water;
DOI:10.1016/j.tet.2021.132535