methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Base Information

Chemical Name:methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt
CAS No.:1232287-16-9
Molecular Formula:C₉H₁₀FNO₂*H₂O₄S
Molecular Weight:281.262
Hs Code.:

Synonyms:methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Suppliers and Price of methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

There total 4 articles about methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1013-88-3
Benzophenone imine

: 861905-21-7
methyl 3-fluoro-5-iodo-4-methylbenzoate

: 1,1'-Bis(diphenylphosphino)ferrocene

: 1232287-18-1
methyl 3-[(diphenylmethylene)amino]-5-fluoro-4-methylbenzoate

: 7440-44-0
pyrographite

: 1232287-16-9
methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Guidance literature:: With sulfuric acid; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In methanol; toluene; acetonitrile;

Reference yield:

: 350-28-7
3-fluoro-4-methyl-benzoic acid

: 1232287-16-9
methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Guidance literature:: Multi-step reaction with 4 steps

1: trifluoroacetic acid; N-iodo-succinimide / -20 °C / Inert atmosphere; Large scale

2: sulfuric acid / 50 °C / Inert atmosphere; Large scale

3: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate / toluene / Reflux; Inert atmosphere; Large scale

4: sulfuric acid / tert-butyl methyl ether; toluene; methanol / Inert atmosphere; Large scale

With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-iodo-succinimide; sulfuric acid; caesium carbonate; trifluoroacetic acid; In methanol; tert-butyl methyl ether; toluene; 3: |Buchwald-Hartwig Coupling;
DOI:10.1021/acs.oprd.1c00283

Reference yield:

: 861905-94-4
3-fluoro-5-iodo-4-methylbenzoic acid

: 1232287-16-9
methyl 3-amino-5-fluoro-4-methylbenzoate sulfuric acid salt

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 50 °C / Inert atmosphere; Large scale

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate / toluene / Reflux; Inert atmosphere; Large scale

3: sulfuric acid / tert-butyl methyl ether; toluene; methanol / Inert atmosphere; Large scale

With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sulfuric acid; caesium carbonate; In methanol; tert-butyl methyl ether; toluene; 2: |Buchwald-Hartwig Coupling;
DOI:10.1021/acs.oprd.1c00283