2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane

Base Information

• Chemical Name: 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane
• CAS No.: 1375466-88-8
• Molecular Formula: C₃₆H₅₂N₄O₂
• Molecular Weight: 572.834
• Mol file: 1375466-88-8.mol

Synonyms:2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane

Chemical Property of 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane

There total 1 articles about 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

α-bromoacetophenone (70-11-1) + 3,14-dimethyl-2,6,13,17-tetraazatricyclo<16.4.01,4.07,12>docosane (138307-72-9) → 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane (1375466-88-8)

Guidance literature:

In chloroform; for 30h; Reflux;

DOI:10.1016/j.ica.2012.02.026

Reference yield: 90.0%

2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane (1375466-88-8) → C36H52N4O2*2ClHO4

Guidance literature:

With perchloric acid; In water; acetonitrile; at 20 ℃; for 1h;

DOI:10.1016/j.ica.2012.02.026

Reference yield: 60.0%

perchloric acid (7601-90-3) + 2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1.18)0(7.12)]docosane (1375466-88-8) + nickel(II) acetate tetrahydrate (6018-89-9) → trans-[(2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1,18)0(7,12)]docosane)Ni](ClO4)2 + cis-[(2,13-bis(2-phenacyl)-5,16-dimethyl-2,6,13,17-tetraazatricyclo[16.4.0.(1,18)0(7,12)]docosane)Ni](ClO4)2

Guidance literature:

In methanol; water; to boiling soln. of Ni-salt in CH3OH macrocycle added, refluxed for 1 h,cooled to room temp., HClO4 and H2O added; soln. stand at room temp., filtered, solid washed (CH3OH), dried (air), recrystd. from 3;1 CH3CN:H2O; elem. anal.;

DOI:10.1016/j.ica.2012.02.026

upstream raw materials:

α-bromoacetophenone

3,14-dimethyl-2,6,13,17-tetraazatricyclo<16.4.0^1,4.0^7,12>docosane